Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy

Giertz, Silvia Helena; Fernandes, Beatriz Luci; Fernandes, Carlos Roberto Corrêa; Franco, Célia Regina Cavichiolo

doi:10.1590/s1516-14392010000100009

Cited by 9 publications

(6 citation statements)

References 18 publications

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“…According to previous research [ 7 ], the results showed that there were some elements of media traces on the material surface, which could affect the biocompatibility properties [ 39 , 40 ]. Therefore, this research also studied the residual elements on the surface to determine whether or not the media of the second shot would be able to stick on the surface in the manner of single shot peening, and whether elements of the first shot can be removed from the second shot or not.…”

Section: Resultsmentioning

confidence: 99%

Effects of the secondary shot in the double shot peening process on the residual compressive stress distribution of Ti–6Al–4V

Ongtrakulkij

Khantachawana

Kajornchaiyakul

et al. 2022

Heliyon

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Double shot peening is the development of shot peening by shooting large media as a first shot and re-shooting again with smaller media as a second shot in order to achieve high residual compressive stress and hardness at the surface, while the in-depth effect can still be maintained. This research aims to examine the effect of media type and media size when used in the second shot of double shot peening on hardness, roughness, and residual stress to identify the suitable conditions and compare them with single shot peening, such as conventional shot peening and fine shot peening, which was used as the first shot and second shot. Ti–6Al–4V was used as the substrate material, while various diameter sizes of silica and SUS304 media were selected as the media for the second shot in the process. The results showed that in the case of the larger size of silica media in the second shot of double shot peening, the hardness and residual compressive stress on the surface clearly increased more than with the smaller media due to the higher Almen intensity, which affected impact energy. On the other hand, when shooting with SUS304 media as a second shot, the increment of residual compressive stress and hardness, including roughness reduction on the surface, showed less effect than was the case for silica media, due to the lower Almen intensity, which affected the impact energy transfer. This research found that the condition of shooting with 80 μm of silica media as the second shot could generate the highest hardness and residual compressive stress on the surface, which increased by 14% and 53%, respectively, while roughness was decreased by 20% when compared with single shot peening.

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Section: Resultsmentioning

confidence: 99%

Effects of the secondary shot in the double shot peening process on the residual compressive stress distribution of Ti–6Al–4V

Ongtrakulkij

Khantachawana

Kajornchaiyakul

et al. 2022

Heliyon

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“…The purpose is to eliminate the residual and unmelted powders on the surface of the original printed sample, to increase the roughness and biological function of the material, and to strengthen the integration of bone tissue and materials. However, with the increasing understanding of the mechanism of wound healing and the response of host cells to biomedical metal materials, speci c "immunoregulatory" metal materials may promote wound healing and osseointegration, which means that residual powders on the surface of 3D printed metal may not be a completely harmful factor [43,44].…”

Section: Effects Of Implant Residual Powder In Vivomentioning

confidence: 99%

Impacts of residual 3D printing metal powders on immunological response and bone regeneration: An in vivo study

Tang

Zhuo²,

Zhang³

et al. 2022

Preprint

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Background Residual powder is a defect in powder bed fusion-based additive manufacturing (3D printing), and it is difficult to completely remove it from as-printed materials. In addition, it is not necessary to apply 3D printed implants with residual powder in the clinic. The immunological response triggered by the residual powder is an important area of study in medical research. Methods To further understand the possible immunological reactions and hidden dangers caused by residual powders in vivo, this study compared the immunological reactions and osteolysis caused by typical powders for four implant materials: 316L stainless steel, CoCrMo, CP-Ti, and Ti-6Al-4V (particle size range of 15–45 µm), in a mouse skull model. Furthermore, the possible immunological responses and bone regeneration induced by the four 3D printed implants with residual powder in a rat femur model were compared. Results In the mouse skull model, it was found that the 316L-S, CoCrMo-S, and especially the 316L-M powders, upregulated the expression of pro-inflammatory factors, increased the ratio of RANKL/OPG, and activated more functional osteoclasts, resulting in more severe bone resorption compared with those in other groups. In the rat femur model, which is more suitable for clinical practice, there is no bone absorption in implants with residual powders, but they show good bone regeneration and integration ability because of their original roughness. The results indicate that the expressions of inflammatory cytokines in all experimental groups were the same as those in the control group, showing good biological safety. Conclusions The results answered some critical questions related to additively manufactured medical materials in vivo and indicated that as-printed implants may have great potential in future clinical applications.

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“…Three input variables (X1: HNO3 concentration, X2: temperature of passivation solution, and X3: passivation time) were selected as passivation parameters. The 3 3 full factorial design with three replications was used. Real and coded values of the parameters and their levels used in the experimentation are given in previous published paper [13].…”

Section: Passivation Processmentioning

confidence: 99%

“…The main disadvantages of this steel are local corrosion susceptibility during prolonged contact with human tissue, and release of metal ions [2]. Additionally, nickel is known as a strong immunological reaction medium and may cause various health problems [3]. Despite the above listed weaknesses, SS has the ability to spontaneously form a stable self-protecting oxide layer (passive film) on its surface in the reaction with air or most aqueous environments.…”

mentioning

confidence: 99%

The effects of passivation parameters on pitting potential of biomedical stainless steel

Petković

Madić

Radenković

2017

CI&CEQ

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Article Highlights • Corrosion resistance of 316LVM stainless steel was increased by passivation • Multiple regression analysis and artificial neural network (ANN) were employed • Only the ANN model provided a statistically accurate mathematical model • Pitting potential is highly non-linearly dependent on the passivation parameters • Nitric acid concentration has the strongest influence on the pitting potential

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Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy

Cited by 9 publications

References 18 publications

Effects of the secondary shot in the double shot peening process on the residual compressive stress distribution of Ti–6Al–4V

Effects of the secondary shot in the double shot peening process on the residual compressive stress distribution of Ti–6Al–4V

Impacts of residual 3D printing metal powders on immunological response and bone regeneration: An in vivo study

The effects of passivation parameters on pitting potential of biomedical stainless steel

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