Nó-de-cachorro (Heteropterys tomentosa A. Juss.): espécie de uso medicinal em Mato Grosso, Brasil

Abstract

RESUMO:Neste estudo é apresentada uma revisão sobre nó-de-cachorro (Heteropterys tomentosa A. Juss.), espécie de uso medicinal em Mato Grosso. São abordadas as características da espécie com a descrição da planta, hábitat, distribuição geográfica, ecologia, fenologia e biologia reprodutiva, propriedades químicas e farmacológicas. Os aspectos como a etnobotânica (uso e partes usadas), formas de exploração atual e informações sobre cultivo são discutidos.Palavras-chave: Malpighiaceae, conservação, cultivo, etnobotânica, cerrado, plantas medicinais ABSTRACT: "Nó-de-cachorro" (Heteropterys tomentosa A. Juss.): a medicinal plant from Mato Grosso State, Brazil. This study presents a review about "Nó-de-cachorro" (Heteropterys tomentosa A. Juss.), a medicinal species from Mato Grosso State, Brazil. We outlined the characteristics of the species including the plant description, habitat, geographic distribution, ecology, phenology and reproductive biology, chemical and pharmacological properties. Aspects such as ethnobotany (use and used parts), current ways of exploiting and information on cultivation are discussed.

Comparison of the chemical composition and biological effects of the roots, branches and leaves of Heteropterys tomentosa A. Juss

“…Heteropterys tomentosa is a species widely used in Brazilian popular medicine and has the potential to be explored by the pharmaceutical industry Coelho et al, 2011). Currently, the active components are almost exclusively obtained by extraction, which compromises the native plant population because root removal leads to plant death.…”

“…Tannins, flavonoids, polyphenols and triterpenoids were also detected in the three parts of the plant, while alkaloids were not found in either the three parts of the plant or in the BST0298 extract by TLC. Previous studies revealed the presence of nitrogen compounds in Heteropterys tomentosa extracts by other techniques (Roman Junior et al, 2005;Coelho et al, 2011), although these have not been evaluated in terms of their adaptogenic activity.…”

“…Mach., given by Othon Machado (Machado, 1949), although the species had previously been described in 1832 by Antoine Laurent de Jussieu. Although some botanists consider the name Heteropterys aphrodisiaca a synonym, this name is considered to be botanically incorrect according to Malpighiaceae specialists (Amorim, 2010;Araú jo et al, 2010;Coelho et al, 2011). Roots such as ''garrafadas'' are chronically used by the population to improve general health due to their preventive effects against a wide range of health conditions (Pott and Pott, 1994;, similar to adaptogenic and tonic plants (Panossian et al, 1999).…”

“…It is important to verify whether other parts of the plant can have the same beneficial effects with lower toxicity. Although the roots are primarily used, there are reports of various uses for the leaves (Coelho et al, 2011). However, there have been no pharmacological studies of the leaves and branches.…”

PHYTOCHEMICAL ANALYSIS OF HYDROETHANOLIC EXTRACTS FROM POWDERED ROOTS OFPanax ginsengC. A. Meyer ANDHeteropterys tomentosaA. Juss AND EVALUATION OF THEIR EFFECTS ON ASTROCYTE CELL DEATH

“…32 The following databases were used for the identification of constituents: Riken MSn spectral database for phytochemicals (ReSpect) (http://spectra.psc.riken.jp/), Phenol-Explorer (www.phenol-explorer. eu), Chem.…”