Allelic frequencies and statistical data obtained from 12 codis STR loci in an admixed population of the Brazilian Amazon

The allelic and haplotype frequencies of 17 Y-STR loci most commonly used in forensic testing were estimated in a sample of 138 unrelated healthy males from Macapá, in the northern Amazon region of Brazil. The average gene diversity was 0.6554 ± 0.3315. 134 haplotypes of the 17 loci were observed, 130 of them unique and four present in two individuals each. The haplotype diversity index was 0.9996 + 0.0009, with the most frequent haplogroups being R1b (52.2%), E1b1b (11.6%), J2 (10.1%) and Q (7.2%). Most haplogroups of this population belonged to European male lineages (89.2%), followed by Amerindian (7.2%) and African (3.6%) lineages.

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“…These observations agree with previous reports (Carvalho-Silva et al , 2001; Silva et al , 2006; Francez et al , 2011). …”

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confidence: 94%

Haplotype diversity of 17 Y-str loci in an admixed population from the Brazilian Amazon

Francez

Ramos²,

Palha

et al. 2011

Genet. Mol. Biol.

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“…Kimura et al (2013); a subset of these communities was also studied for two Alu insertions, and the values used to estimate parental contributions (Cotrim et al , 2004), but the results obtained showed inconsistencies among the populations and were not considered; 10. Francez et al (2011a); 11. Francez et al (2011b); 12.…”

Section: Tablementioning

confidence: 99%

Interethnic admixture and the evolution of Latin American populations

2014

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A general introduction to the origins and history of Latin American populations is followed by a systematic review of the data from molecular autosomal assessments of the ethnic/continental (European, African, Amerindian) ancestries for 24 Latin American countries or territories. The data surveyed are of varying quality but provide a general picture of the present constitution of these populations. A brief discussion about the applications of these results (admixture mapping) is also provided. Latin American populations can be viewed as natural experiments for the investigation of unique anthropological and epidemiological issues.

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“…Analysis of allele frequencies using short-tandem repeat (STR) markers has been published by several research groups in various Brazilian regions, including the Amazon region (Francez et al, 2011), Northeast region (Ferreira da Silva et al, 2002), Southeast region (Silva et al, 2004;Goís et al, 2006), South region (Leite et al, 2006) and even in the Midwest, such as in Mato Grosso do Sul (Silva et al, 2004). Due to the miscegenation of Brazil, its central region was colonized by internal migration, with the settling of Goiás State initiated in the 19th century (Fausto, 2006).…”

Section: Introductionmentioning

confidence: 99%

Short Communication Allelic frequencies and statistical data obtained from 15 STR loci in a population of the Goiás State

Vieira¹,

Silva²,

Gigonzac³

et al. 2013

Genet. Mol. Res.

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ABSTRACT. Due to the miscegenation of the Brazilian population, the central region of Brazil was colonized by internal migration of individuals from different origins, who contributed to the genetic diversity existing in this population. The purpose of this study was to estimate population parameters based on the allele frequencies for 15 polymorphic autosomal short-tandem repeat (STR) loci present in the population of the State of Goiás in the central region of Brazil, and to compare the results with those of others from different Brazilian populations. DNA was obtained from a sample of 986 unrelated individuals by a commercial reagent kit and was quantified by spectrometry for later amplification in the thermocycler. These loci, commonly used in forensics and paternity testing, reflected Hardy-Weinberg equilibrium in this population. The D18S51 and Penta E loci had the highest number of alleles, while the observed heterozygosity reached the highest rates in FGA (0.920), D7S820 (0.870), and vWA (0.867) markers. Genetic diversity reached the highest levels in Penta E (0.906), Penta D (0.873), and D18S51 (0.860) markers, and the investigated forensic parameters showed high average values, with 93% power of discrimination, polymorphism information content of 78%, gene diversity of 79%, and observed heterozygosity of 79%. Similar to the other populations of Brazil, the population of the Midwest is derived from the admixture of 3 main parental groups: Amerindian, European, particularly Portuguese, and Africans from sub-Saharan Africa. In this context, the overall distribution of allele frequencies in the STR markers of various Brazilian populations is quite similar to the data obtained in this study.

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Allelic frequencies and statistical data obtained from 12 codis STR loci in an admixed population of the Brazilian Amazon

Cited by 13 publications

References 11 publications

Haplotype diversity of 17 Y-str loci in an admixed population from the Brazilian Amazon

Haplotype diversity of 17 Y-str loci in an admixed population from the Brazilian Amazon

Interethnic admixture and the evolution of Latin American populations

Short Communication Allelic frequencies and statistical data obtained from 15 STR loci in a population of the Goiás State

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