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“…Post-feeding hyperammonaemia in the mesenteric blood was found in patients with liver cirrhosis. 31 Similarly, Kogika et al 32 found a significant difference in pre- and postprandial ammonia levels in the fresh plasma from healthy cats. However, when Walker et al 33 performed ammonia tolerance tests on venous blood of healthy dogs and dogs with suspected liver disease, they concluded that ammonia measurement is a useful test to diagnose congenital portosystemic vascular abnormalities, but that it has poor sensitivity in detecting hepatocellular disease.…”
Section: Discussionmentioning
confidence: 90%
“…Post-feeding hyperammonaemia in the mesenteric blood was found in patients with liver cirrhosis. 31 Similarly, Kogika et al 32 found a significant difference in pre- and postprandial ammonia levels in the fresh plasma from healthy cats. However, when Walker et al 33 performed ammonia tolerance tests on venous blood of healthy dogs and dogs with suspected liver disease, they concluded that ammonia measurement is a useful test to diagnose congenital portosystemic vascular abnormalities, but that it has poor sensitivity in detecting hepatocellular disease.…”
Section: Discussionmentioning
confidence: 90%
“…A amônia foi mensurada no plasma em até 30 minutos após a colheita de sangue em tubo heparinizado, sendo o plasma conservado à temperatura de -20ºC até o momento da análise (KOGIKA et al, 1999 A desintoxicação da amônia é de extrema importância para a manutenção da homeostase e, esta ocorre principalmente por meio de duas vias principais, ciclo da ureia e síntese de glutamina, ambas no fígado. O ciclo da ureia é uma sequência de reações bioquímicas que convertem a amônia em ureia, responsável pelo descarte de mais de 90% do nitrogênio excedente proveniente de fontes endógenas ou alimentares (ROSKAMS et al, 2007 As globulinas séricas totais representam a soma das imunoglobulinas e das não imunoglobulinas e, muitas delas são sintetizadas e armazenadas no fígado.…”
Section: Amôniaunclassified