2010
DOI: 10.1590/s1413-86702010000300006
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Abstract: We concluded that the predominant strain of HIV-1 in Paraná is subtype B, followed by subtype C. Some mutations at PR and TR had subtype predominance in accordance with other authors' report.

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Cited by 9 publications
(4 citation statements)
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References 36 publications
(49 reference statements)
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“…These data suggest an increase of subtype C frequency over time. Also, Toledo et al (2010) had similar results when they reported the HIV-1 subtype profile from adult patients in failure therapy in PR. Clade B was found in 61% of cases and clade C in 20% of the cases.…”
Section: Discussionsupporting
confidence: 52%
“…These data suggest an increase of subtype C frequency over time. Also, Toledo et al (2010) had similar results when they reported the HIV-1 subtype profile from adult patients in failure therapy in PR. Clade B was found in 61% of cases and clade C in 20% of the cases.…”
Section: Discussionsupporting
confidence: 52%
“…These observations may reveal a different efficacy of homosexual/heterosexual transmission of subtypes B and C, or may reflect different entries and dissemination networks of these subtypes in Santa Catarina. The high proportion of subtype B among females in Rio Grande do Sul and Paraná (38-42%), 12,17 and the recent expansion of subtype C among MSM in São Paulo (Brazil), 34 strongly favor the second hypothesis.…”
Section: Discussionmentioning
confidence: 97%
“…1 The Brazilian HIV-1 epidemic can be divided in two distinct scenarios. While subtype B prevails in most of the Country, with a secondary occurrence of subtype F1 and BF1 recombinants, [2][3][4][5][6][7][8][9] Southern Brazil presents a distinct pattern with high frequency of subtypes C, B and BC recombinants, following a lower proportion of subtype F1 and BF1 recombinants, [10][11][12][13][14][15][16][17] comprising 19% of the infected individuals in the Country. The universal access of Brazilian HIV-positive patients to freeof-cost licensed antiretroviral drugs has substantially reduced the AIDS-related mortality.…”
Section: Introductionmentioning
confidence: 99%
“…States from the south region (Rio Grande do Sul, Santa Catarina and Paraná), which concentrate 20% of the Brazilian AIDS cases [1], display a distinct molecular epidemiology profile characterized by the high prevalence of subtypes C, B and BC recombinants. It has been estimated that subtype C represents around 20–30% of HIV-1 infections in Paraná [3], [7], [8], [9], [10], 30–45% of HIV-1 infections in Rio Grande do Sul [3], [11], [12], [13], [14], [15], and 50–80% of HIV-1 infections in Santa Catarina [14], [16], [17], [18].…”
Section: Introductionmentioning
confidence: 99%