Molecular epidemiology of Acinetobacter baumannii in central intensive care unit in Kosova teaching hospital

Raka, Lul; Kalenc, Smilja; Bošnjak, Zrinka; Budimir, Ana; Katić, Stjepan; Šijak, Dubravko; Mulliqi‐Osmani, Gjyle; Zoutman, Dick; Jaka, Arbëresha

doi:10.1590/s1413-86702009000600004

“…In this study, majority 12(86%) of the isolates were recovered from tracheal aspirate. This finding is similar to the 87% observed by Raka et al (2004) but much higher than 46.5% reported by Popescu et al (2011). The high rate of recovery from the respiratory tract may be due to the invasive procedures that are carried out in the respiratory tract in the process of maintaining the airway.…”

Section: Discussionsupporting

confidence: 91%

“…The observed prevalence is higher than reports from similar studies carried out in France by Joly-Guillou (2005) who reported 9% and Iregbu et al (2002) who reported 4.6% in Lagos, Nigeria (Iregbu et al, 2002). Acinetobacter constituted 9% of all isolates in the study, this finding is low compared to 14.5% obtained by Kessaris et al (2006), 13.9% by Raka et al (2004) but higher than 8.4% reported by Oberoi et al (2009) and 3% reported by Iregbu et al (2002). This may be because their study included all patients in the hospital compared to this study which was limited to the ICU.…”

Section: Discussioncontrasting

confidence: 66%

“…Outbreaks of Acinetobacter infections are linked to contaminated respiratory equipment, intravascular access devices, bedding materials and transmission via hands of hospital personnel. Acinetobacter outbreaks have been traced to commonsource contamination, particularly contaminated respiratory-therapy and ventilator equipment, crossinfection by the hands of health care workers who have cared for colonized or infected patients or touched contaminated formite and to the occasional health care worker who carries an epidemic strain (Raka et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

NOSOCOMIAL <i>ACINETOBACTER</i> INFECTIONS IN INTENSIVE CARE UNIT

Ugochukwu¹,

Adetona

²

,

Fowotade

³

et al. 2013

American Journal of Infectious Diseases

2

1

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Acinetobacter plays an important role in the infection of patients admitted to hospitals. Acinetobacter are free living gram-negative coccobacilli that emerge as significant nosocomial pathogens in the hospital setting and are responsible for intermittent outbreaks in the Intensive Care Unit. The aim of this study was to determine the prevalence of Acinetobacter in patients admitted into the Intensive Care Unit and determine their role in infections in the ICU. A total of one hundred patients were recruited for the study, catheter specimen urine, tracheal aspirate and blood culture were collected aseptically from the patients. The specimens were cultured on blood and MacConkey and the organisms identified using Microbact 12E (0xoid). The Plasmid analysis was done using the TENS miniprep method. Fourteen (14%) of the 100 patients recruited into the study, developed Acinetobacter infection. Acinetobacter spp constituted 9% of the total number of isolates. Twelve (86%) of the isolates were recovered from tracheal aspirate, 1(7%) from urine and 1(7%) from blood. All of the isolates harbor plasmids of varying molecular sizes. Ten of the fourteen Acinetobacter were isolated at about the same period of time in the ICU with 6(42.7%) having plasmid size in the 23.1kb band and all showed similar pattern revealing that the isolates exhibit some relatedness. The clonal nature of the isolates suggest that strict infection control practices must be adopted in ICU, also an antibiotic policy must be developed for the ICU to prevent abuse of antibiotics that may lead to selection of resistant bacteria.

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“…Acinetobacter constituted 9% of all isolates in the study, this finding is low compared to 14.5% obtained by Kessaris et al (2006), 13.9% by Raka et al (2004) but higher than 8.4% reported by Oberoi et al (2009) and 3% reported by Iregbu et al (2002). This may be because their study included all patients in the hospital compared to this study which was limited to the ICU.…”

Section: Ajidcontrasting

confidence: 63%

NOSOCOMIAL <I>ACINETOBACTER</I> INFECTIONS IN A TERTIARY FACILITY

Ugochukwu¹,

SAdetona²,

Fowotade³

et al. 2012

American Journal of Infectious Diseases

0

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Acinetobacter plays an important role in the infection of patients admitted to hospitals. Acinetobacter are free living gram-negative coccobacilli that emerge as significant nosocomial pathogens in the hospital setting and are responsible for intermittent outbreaks in the Intensive Care Unit. The aim of this study was to determine the prevalence of Acinetobacter in patients admitted into the Intensive Care Unit and determine their role in infections in the ICU. A total of one hundred patients were recruited for the study, catheter specimen urine, tracheal aspirate and blood culture were collected aseptically from the patients. The specimens were cultured on blood and MacConkey and the organisms identified using Microbact 12E (0xoid). The Plasmid analysis was done using the TENS miniprep method. Fourteen (14%) of the 100 patients recruited into the study, developed Acinetobacter infection. Acinetobacter spp constituted 9% of the total number of isolates. Twelve (86%) of the isolates were recovered from tracheal aspirate, 1(7%) from urine and 1(7%) from blood. All of the isolates harbor plasmids of varying molecular sizes. Ten of the fourteen Acinetobacter were isolated at about the same period of time in the ICU with 6(42.7%) having plasmid size in the 23.1kb band and all showed similar pattern revealing that the isolates exhibit some relatedness. The clonal nature of the isolates suggest that strict infection control practices must be adopted in ICU, also an antibiotic policy must be developed for the ICU to prevent abuse of antibiotics that may lead to selection of resistant bacteria.

show abstract

“…The Acinetobacter genomic species emerged as a major problem in the 1990s, and it has even become the micro-organism most frequently associated with pneumonia, catheter infections and meningitis in some public and private hospitals (Toledo et al, 2012). The emergence of Acinetobacter has been attributed to not only bacterial characteristics such as survival for long periods on surfaces and medical equipment but also its association with person-to-person transmission (Pilonetto et al, 2004;Raka et al, 2009;Medell et al, 2012).…”

Section: Introductionmentioning

confidence: 99%