2005
DOI: 10.1590/s1413-86702005000500010
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Abstract: Cutaneous manifestations in disseminated strongyloidiasis are infrequent but should raise the suspicion for its diagnosis. We retrospectively evaluated the charts of six patients with cancer and a proven diagnosis of disseminated strongyloidiasis. All patients had received prophylaxis with albendazole before starting antineoplastic therapy, which included high-dose steroids. They presented with septic shock, acute respiratory failure and characteristic purpuric periumbilical skin lesions. Strongyloides larvae … Show more

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Cited by 38 publications
(25 citation statements)
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“…Hyperinfection syndrome (HIS) occurs when chronically infected individuals are administered corticosteroids, resulting in increased numbers of larvae and exacerbation of gastrointestinal and pulmonary symptoms [5]. DS occurs when large numbers of larvae migrate beyond from the gastrointestinal tract and lungs to ectopic sites such as the skin, as occurred in our patient [6]. The mortality associated with HIS or disseminated disease approaches 100% if untreated [5].…”
Section: Discussionmentioning
confidence: 99%
“…Hyperinfection syndrome (HIS) occurs when chronically infected individuals are administered corticosteroids, resulting in increased numbers of larvae and exacerbation of gastrointestinal and pulmonary symptoms [5]. DS occurs when large numbers of larvae migrate beyond from the gastrointestinal tract and lungs to ectopic sites such as the skin, as occurred in our patient [6]. The mortality associated with HIS or disseminated disease approaches 100% if untreated [5].…”
Section: Discussionmentioning
confidence: 99%
“…19,64 This skin finding is characterized by serpiginous, pruritic urticarial wheals that have been documented to travel as the result of fastmoving larvae. 21 Petechiae and purpura have also been reported in disseminated cases of S stercoralis [65][66][67] and are thought to be the result of larvae migration through vessel walls causing hemorrhage. 66 This has classically been referred to as ''thumbprint purpura'' and is often found on the trunk as was observed in our patient.…”
Section: Discussionmentioning
confidence: 99%
“…Cutaneous periumbilical purpura has been described in patients with disseminated disease due to migration of larvae through vessel walls in the dermis [24]. The syndrome of inappropriate secretion of antidiuretic hormone has also been associated with disseminated infection [25].…”
Section: Hyperinfection Syndrome/disseminated Strongyloidiasismentioning
confidence: 99%