Estudo sobre a associação de cerâmica a plasma rico em plaquetas na coluna vertebral de ratos

Delgado, Rita; Bonatelli, Antônio de Pádua Furquim; Alves, Maria Teresa de Seixas

doi:10.1590/s1413-78522009000500006

Cited by 4 publications

(1 citation statement)

References 11 publications

(8 reference statements)

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“…The sessions were conducted daily, 8 animals at a time, and began on the first post-operative day for 90 minutes at 3 ATA (13). We opted for 9 sessions in the HBO and APC+HBO groups because the growth factor acts primarily during the first 7 post-operative days (14). …”

Section: Methodsmentioning

confidence: 99%

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Neves¹,

Abib²,

Neves³

et al. 2013

Clinics

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OBJECTIVES:The purpose is to study the effects of hyperbaric oxygen therapy and autologous platelet concentrates in healing the fibula bone of rabbits after induced fractures.METHODS:A total of 128 male New Zealand albino rabbits, between 6–8 months old, were subjected to a total osteotomy of the proximal portion of the right fibula. After surgery, the animals were divided into four groups (n = 32 each): control group, in which animals were subjected to osteotomy; autologous platelet concentrate group, in which animals were subjected to osteotomy and autologous platelet concentrate applied at the fracture site; hyperbaric oxygen group, in which animals were subjected to osteotomy and 9 consecutive daily hyperbaric oxygen therapy sessions; and autologous platelet concentrate and hyperbaric oxygen group, in which animals were subjected to osteotomy, autologous platelet concentrate applied at the fracture site, and 9 consecutive daily hyperbaric oxygen therapy sessions. Each group was divided into 4 subgroups according to a pre-determined euthanasia time points: 2, 4, 6, and 8 weeks postoperative. After euthanasia at a specific time point, the fibula containing the osseous callus was prepared histologically and stained with hematoxylin and eosin or picrosirius red.RESULTS:Autologous platelet concentrates and hyperbaric oxygen therapy, applied together or separately, increased the rate of bone healing compared with the control group.CONCLUSION:Hyperbaric oxygen therapy and autologous platelet concentrate combined increased the rate of bone healing in this experimental model.

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Section: Methodsmentioning

confidence: 99%

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Neves¹,

Abib²,

Neves³

et al. 2013

Clinics

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Avaliação da eficácia do plasma rico em plaquetas na consolidação óssea de pacientes submetidos a artrodese lombar

Rezende¹,

Azevedo²,

Lourenço³

et al. 2017

Revista Brasileira de Ortopedia

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Evaluation of the effectiveness of platelet-rich plasma in the bone consolidation of patients submitted to lumbar arthrodesis

Rezende

Azevedo

Lourenço³

et al. 2017

Revista Brasileira de Ortopedia (English Edition)

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ObjectiveTo determine whether the use of autograft associated with platelet-rich plasma (PRP) increases bone healing in patients undergoing lumbar fusion.MethodThis was a prospective, descriptive, and comparative study, which included 40 patients undergoing lumbar fusion, who were divided into two groups: group I, autograft only, and group II, autograft associated with PRP. After surgery, patients were followed-up on the first, third, and sixth month. The Molinari radiographic classification and Glassman tomographic classification were used as criteria to analyze the bone consolidation.ResultComparing the group I with group II, according to the criteria of Molinari, bilateral fusion was observed in 27.5% of the patients in group I in the first month after surgery. In group II, the rate of bilateral fusion was 25.0% and 20% in the third and sixth months, respectively. The results of computed tomography scans performed at six months after surgery indicated, according to the criteria of Glassman, a rate of bilateral solid fusion of 15.0% and 10.0% in groups I and II, respectively.ConclusionThe use of PRP showed no significant difference in bone healing in cases of lumbar arthrodesis.

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Estudo sobre a associação de cerâmica a plasma rico em plaquetas na coluna vertebral de ratos

Cited by 4 publications

References 11 publications

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing

Avaliação da eficácia do plasma rico em plaquetas na consolidação óssea de pacientes submetidos a artrodese lombar

Evaluation of the effectiveness of platelet-rich plasma in the bone consolidation of patients submitted to lumbar arthrodesis

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