Abstract:ResumoA ativação farmacológica dos receptores 5-HT 2C induz comportamentos de defesa em modelos animais. O estudo busca investigar se o bloqueio seletivo de receptores 5-HT 2C no hipocampo ventral (HV) previne comportamentos defensivos induzidos por um agonista de receptor 5-HT 2C administrado perifericamente em ratos expostos ao labirinto em cruz elevado (LCE). Quinze minutos após injeções intraperitoniais (IP, 1ml/ kg) do agonista 5-HT 2C WAY-161503, ratos foram microinjetados bilateralmente no HV com o anta… Show more
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