2010
DOI: 10.1590/s0482-50042010000400011
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Piomiosite associada ao diabetes mellitus e cirrose hepática

Abstract: Pyomyositis is a primary infection of the skeletal muscle, occurring most commonly in tropical countries. Adults who develop the disease have, in most cases, associated comorbidities that compromise the immune system, including diabetes mellitus and liver cirrhosis.

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Cited by 2 publications
(4 citation statements)
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References 6 publications
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“…Other conditions listed as risk factors were organ transplant, malnutrition, chronic kidney disease, and rheumatoid arthritis. Though the pathophysiology is not fully explained, there are case reports of cirrhosis and even hepatitis C, both of which impair the immunity, associated with pyomyositis [6][7][8][9]. Interestingly, obesity also demonstrated to increase the risk, with morbid obesity being higher risk (1.47) than obesity (1.34).…”
Section: Discussionmentioning
confidence: 99%
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“…Other conditions listed as risk factors were organ transplant, malnutrition, chronic kidney disease, and rheumatoid arthritis. Though the pathophysiology is not fully explained, there are case reports of cirrhosis and even hepatitis C, both of which impair the immunity, associated with pyomyositis [6][7][8][9]. Interestingly, obesity also demonstrated to increase the risk, with morbid obesity being higher risk (1.47) than obesity (1.34).…”
Section: Discussionmentioning
confidence: 99%
“…In our case, the patient had a prolonged period of bacte-remia and developed pyomyositis despite initial appropriate therapy. The patient had several conditions known to impact the immune system negatively, including diabetes mellitus, cirrhosis, and hepatitis C [6,7,9]. Both cirrhosis and hepatitis C affect the innate and adaptive immune response [12,13].…”
Section: Discussionmentioning
confidence: 99%
“…Por ello, el aumento en su prevalencia puede ser importante en el riesgo de comorbilidades infecciosas, como la TB. La hiperglicemia y la insulinopenia celular, así como los efectos indirectos en la afectación de la quimiotaxis, fagocitosis, activación y presentación de antígenos, de linfocitos y macrófagos, predisponen a la TB (1) , pero también a infecciones como la piomiositis (2) e incluso parasitosis como la estrongiloidiasis y la malaria (3,4) .…”
unclassified
“…Es de notar que en abril de 2014, la OMS publicó un informe donde se estima que la contaminación del aire exterior era responsable de la muerte de unos 3,7 millones de personas menores de 60 años a nivel global (2) . Dado los hallazgos de la pendiente exposición-respuesta (PM 2,5-muerte) de otros países (3) , y el nivel promedio de PM 2,5 en el aire de Lima en los últimos 10 años, en exceso a la norma de OMS (50 ug/m 3 frente a 10 ug/m 3 ), estimamos que el riesgo relativo de los habitantes de Lima para la muerte cardiopulmonar sería 1,25.…”
unclassified