2010
DOI: 10.1590/s0482-50042010000100002
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Osteonecrose de mandíbula em pacientes com lúpus eritematoso sistêmico juvenil observada em exame de imagem

Abstract: Juvenile systemic lupus erythematosus (JSLE) is an autoimmune disorder affecting several organs and systems, with a wide range of manifestations that can involve the masticatory system and oral mucosa. 1,2 Orofacial involvement in JSLE has not been the focus of a large number of studies. In a recent study, we evaluated 48 patients with JSLE versus 48 age-and gender-matched healthy individuals, and we identified higher incidence of bacterial plaque and gingival bleeding in lupus patients. 3

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Cited by 6 publications
(2 citation statements)
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“…In the polyarticular type, these alterations are more prominent when compared to other subtypes. 21,22 The time of disease onset also has a strong infl uence on abnormal mandibular growth, 23 as the earlier the disease starts, the greater the likelihood of occurrence of adverse effects caused by the treatment and the degenerative effects of the underlying disease on the normal development of the mandible, as described above.…”
Section: Tmj Impairment and Orofacial Effectsmentioning
confidence: 99%
See 1 more Smart Citation
“…In the polyarticular type, these alterations are more prominent when compared to other subtypes. 21,22 The time of disease onset also has a strong infl uence on abnormal mandibular growth, 23 as the earlier the disease starts, the greater the likelihood of occurrence of adverse effects caused by the treatment and the degenerative effects of the underlying disease on the normal development of the mandible, as described above.…”
Section: Tmj Impairment and Orofacial Effectsmentioning
confidence: 99%
“…MRI is considered the best form of early diagnosis, as it can detect alterations in muscle, synovial cartilage, and bone, even in early phases. 24,21 The only disadvantage of MRI is the fact that very young patients need to be sedated for the examination. 12,22,25 Panoramic radiography has advantages such as low cost, low radiation, and reliability, but it only allows the visualization of lesions at a later phase, when the condylar erosions are already established.…”
Section: Diagnosis Of Alterations In the Tmjmentioning
confidence: 99%