Manifestações cutâneas decorrentes do uso de drogas ilícitas

Bittencourt, Flávia Vasques; Lourenço, Lívia Flávia Sebe

doi:10.1590/s0365-05962006000400002

Cited by 10 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Subcutaneous or intramuscular drug injection, particularly with black tar heroin, has been found to be an independent risk factor for bacterial SSTIs in several studies 13,16,19,30–32 . Skin and soft tissue infections occur more commonly secondary to SP than IV drug use because of the direct inoculation of bacteria into the patient's body 12,17 . In addition, bacteria from subcutaneous or intramuscular injections bypass the blood-borne immunologic response typical in IV injection 33 .…”

Section: Discussionmentioning

confidence: 99%

“…The classic acute wounds of SP result from concentric or irregular circles of cutaneous necrosis and are often found incidentally on examination. [17][18][19] Subcutaneous drug injection creates an anaerobic pocket within the dermis, promoting the growth of anaerobic bacteria such as Clostridia species. As such, a prominent risk factor for abscess formation is the use of unsterilized needles.…”

Section: Pathogenesismentioning

confidence: 99%

“…13,16,19,[30][31][32] Skin and soft tissue infections occur more commonly secondary to SP than IV drug use because of the direct inoculation of bacteria into the patient's body. 12,17 In addition, bacteria from subcutaneous or intramuscular injections bypass the blood-borne immunologic response typical in IV injection. 33 Skin and soft tissue infections secondary to SP are typically multilobulated with deeper extension into surrounding tissue and are associated with more significant necrosis than non-IV drug users.…”

Section: Patient Presentationmentioning

confidence: 99%

See 2 more Smart Citations

Skin Popping for the Hand Surgeon

Shih

Francoisse

et al. 2023

Ann Plast Surg

View full text Add to dashboard Cite

Introduction Subcutaneous injection of illicit drugs, colloquially known as skin popping, is associated with skin and soft tissue infections of the upper extremity. Sequelae of these infections often present to hand surgeons in the late stages of disease, are associated with challenging clinical scenarios, and are a significant burden to both patients and providers. The authors present an illustrative case and review the literature regarding this growing phenomenon in upper extremity surgery. Methods A case report detailing the surgical reconstruction of a large forearm wound in the setting of intravenous heroin use and skin popping is presented. Search terms related to upper extremity subcutaneous drug injection were used to find relevant articles in PubMed and EMBASE. A total of 488 articles were found, with 22 studies meeting the inclusion criteria. Results In this case report, the patient had a long history of skin popping to the forearm and presented with a chronic wound with exposed bone. The patient was treated with serial debridement, bony fixation, intravenous antibiotics, and soft tissue coverage using an arteriovenous loop and a muscle-only latissimus flap. Literature review yielded 22 studies comprising 38 patients with 55% (11/20) women and age range of 23 to 58 years. Heroin was the most commonly used drug (50.0%). The most common presentation was soft tissue infection (6/20 patients), manifestations of noninfected wounds (5/20), and wound botulism (4/20 of patients). Seventy percent of patients presented with multiple injection sites. Surgical management was described in 18% of cases, with all but one case describing drainage and debridement techniques. Only one case of formal reconstruction using a dermal template was described. Conclusions Skin popping infections have unique pathogenesis, presentation, and management patterns that hand surgeons must be aware of when treating these patients. A literature review revealed a relative paucity of reports regarding risk factors and surgical management of “skin popping” sequelae. If patients are reconstructive candidates, complex reconstruction requiring free tissue transfer may be warranted.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Pathogenesismentioning

confidence: 99%

Section: Patient Presentationmentioning

confidence: 99%

See 1 more Smart Citation

Skin Popping for the Hand Surgeon

Shih

Francoisse

et al. 2023

Ann Plast Surg

View full text Add to dashboard Cite

show abstract

“…16 Além disso, a maconha tem a capacidade de provocar efeitos no sistema nervoso parassimpático que, em associação ao uso dos anestésicos locais com vasoconstrictores utilizados na clínica odontológica, pode induzir à taquicardia no paciente. 17…”

Section: Maconhaunclassified