Você conhece esta síndrome?

Abstract

A síndrome de Ascher (SA), um subtipo de0 anetodermia, é rara e caracterizada por apresentar em associação, com maior ou menor expressividade, relaxamento da pele das pálpebras, edema de lábio superior e aumento da tireóide. A etiologia é desconhecida, mas há evidências de defeito nas fibras elásticas, que se apresentam fragmentadas ou diminuídas. Relata-se o caso de paciente de 16 anos de idade, com queixa única: episódios recorrentes de edema bipalpebral.

Double Lip Surgical Correction in Ascher’s Syndrome: Diagnosis and Treatment of a Rare Condition

“…In Ascher’s syndrome, it is present in 10 to 50% of cases. 3 , 10 In our report, the patient presented with normal thyroid function.…”

“…6 , 12 , 13 Some cases start the treatment with Dapsone 50 mg/day to delay progression of the syndrome. 10 In our case, the double lip was corrected surgically through a transverse elliptical incision.…”

A Century of Laffer-Ascher Syndrome

“…These structures are developed from the neural crest and mesoderm between weeks 6 and 9. 32 The upper eyelid is developed from the frontonasal process derived from the neural crest and the lower eyelid is developed from the maxillary process. The upper lip is developed from the maxillary processes, the lateral nasal prominences and the intermaxillary segment, and the lower lip from the mandibular process.…”