2001
DOI: 10.1590/s0104-79302001000200008
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Abstract: Toad envenoming in dogs can cause death by cardiac fibrilation (CVF). Traditional therapy consists mainly of atropine and propranolol, the last one used to prevent the CVF, that is preceded by negative ventricular deflections (NVDs) in the QRS complex of the electrocardiogram. This study intended to verify, comparatively, the lidocaine, propranolol, amiodarone, and verapamil abilities to prevent CVF in experimentally envenomed dogs. Thirty-six dogs were divided into 6 groups (GL, GP, GA, GV, GST, and GSV) with… Show more

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Cited by 9 publications
(12 citation statements)
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“…According to this author, this β-blocker has shown an outstanding capacity to reverse cardiac changes and prevent ventricular fibrillation in dogs subjected to experimental toad poisoning. Some researchers have recommended the use of propranolol as bolus and/or continuous infusion (12,5). In the present study, the propranolol efficacy at the dose of 0.5 mg/kg IV was evidenced in the treatment of ventricular arrhythmias caused by toad venom.…”
Section: Discussionmentioning
confidence: 54%
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“…According to this author, this β-blocker has shown an outstanding capacity to reverse cardiac changes and prevent ventricular fibrillation in dogs subjected to experimental toad poisoning. Some researchers have recommended the use of propranolol as bolus and/or continuous infusion (12,5). In the present study, the propranolol efficacy at the dose of 0.5 mg/kg IV was evidenced in the treatment of ventricular arrhythmias caused by toad venom.…”
Section: Discussionmentioning
confidence: 54%
“…Toads (order Anura, family Bufonidae, and genus Bufo) have a worldwide distribution, preferably in tropical and humid temperate climate (4,5). Accidental toad poisoning may occur in dogs, especially in the surroundings of lakes, reservoirs, creeks and rivers, which are the natural habitats of toads (6).…”
Section: Introductionmentioning
confidence: 99%
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“…O sapo do gênero Bufo possui distribuição mundial, porém, existem mais espécies em áreas de clima tropical e úmido, existindo mais de 200 espécies de Bufo em todo o mundo (ROBERTS et al, 2000;SAKATE & OLIVEIRA, 2001). Como mecanismo de defesa contra seus predadores, o sapo do gênero Bufo possui glândulas paratóides localizadas na região posterior à órbita ocular que produzem e estocam um líquido mucoso e esbranquiçado (SAKATE & OLIVEIRA, 2000).…”
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“…A morte destes cães está relacionada ao efeito cardiotóxico do veneno levando à morte por fibrilação ventricular (OSWEILER, 1995;SAKATE & OLIVEIRA, 2000). A manifestação dos sinais clínicos se dá rapidamente após a intoxicação, sendo que a morte pode ocorrer 15 minutos após o aparecimento dos sinais clínicos (SAKATE & OLIVEIRA, 2001).…”
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