“…) (Da-Costa et al, 1997;Baptisa-Neto et al, 2005). Therefore, continuous culture systems have been widely used to cultivate microbes for industrial and research purposes (Zangirolami et al, 2002;Viegas et al, 2002;Kim et al, 2004;Neto et al, 2005;Dominguez et al, 2009). Few studies have been reported on the continuous production of xylanases with bacteria and fungi, mainly because of the problems associated with media containing insoluble xylan substrates (Tangnu et al, 1981;Rőthlisberger et al, 1992).…”