2000
DOI: 10.1590/s0104-66322000000300002
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Abstract: Extraction with supercritical solvents has been used in different areas, such as petroleum desasphaltation, descaffeination of coffee and tea and in the separation of other types of natural products. The supercritical solvent most frequently utilized in the extraction of natural products is carbon dioxide (CO2) due to its several advantages over other solvents such as low cost, atoxicity and volatility. The design, evaluation and optimization of a supercritical extraction that is based on phase equilibrium req… Show more

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Cited by 4 publications
(2 citation statements)
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“…Unfortunately, this method has been limited to those solvation properties where sufficient data are available to assign the necessary fragment contributions, such as the octanol-water partition log P oct , 2 the aqueous solubility log S w , 3 and solubility in polymers 4 and supercritical CO 2 . 5 Unfortunately, other properties of much interest, particularly those related to biological transport, remain inaccessible to such methods, since a minimum requirement is a data set numbering at least several hundred compounds.…”
Section: Introductionmentioning
confidence: 99%
“…Unfortunately, this method has been limited to those solvation properties where sufficient data are available to assign the necessary fragment contributions, such as the octanol-water partition log P oct , 2 the aqueous solubility log S w , 3 and solubility in polymers 4 and supercritical CO 2 . 5 Unfortunately, other properties of much interest, particularly those related to biological transport, remain inaccessible to such methods, since a minimum requirement is a data set numbering at least several hundred compounds.…”
Section: Introductionmentioning
confidence: 99%
“…The sources of the reference data classified as discussed above were: analytical methods [6-9,34-38, ; extraction [2,[4][5][10][11]18,19,21,22,[24][25][26][27][28][29][31][32][33][39][40][41]45,50,52,53,55,[57][58][59]61,62,66,; thermodynamics and fundamental studies [3,[12][13][14][15][16][17]20,23,30,[42][43][44][46][47][48][49]51,54,56,60,[63][64][166][167][168]…”
Section: Historical Factsmentioning
confidence: 99%