Erradicação da poliomielite no Brasil: a contribuição da Fundação Oswaldo Cruz

Abstract

The eradication of wild polioviruses from the Americas represents a remarkable public health achievement. Oswaldo Cruz Foundation (Fiocruz) contributed to this result in many ways. Its National Reference Center for Enteroviruses in the Department of Virology of Oswaldo Cruz Institute developed laboratory activities, Bio-Manguinhos developed and delivered the oral vaccine, its National School of Public Health developed epidemiological and laboratory activities and its National Institute for Quality Control in Health controlled the vaccine. Fiocruz also carried out important research projects on enteroviruses. Since poliomyelitis still represents a serious problem in many countries in the world, it is important to emphasize the relevant contribution of Fiocruz to the eradication of the disease in Brazil and in the American continent.

Esquizofrenia: Uma Revisão De Literatura Com Novas Perspectivas De Tratamento

“…No presente estudo, foi observado que a maioria dos casos notificados de PFA ocorreu em pessoas residentes da zona urbana, além disso, foi constatado que esses casos não estavam associados à poliomielite, conforme revelou o diagnostico laboratorial (Tabela 1). Schatzmayr et al (2002) revelam que a maioria dos casos de PFA estão relacionados à falta de saneamento básico e condições de higiene adequada para a população. Os autores observaram na região Nordeste, casos de PFA em áreas urbanas com baixo nível de saneamento básico.…”

Complete Genome Sequence of the Last Representative Genotype of Wild Indigenous Poliovirus Type 1, Which Circulated in Brazil

“…The incidence of poliomyelitis dropped from an average of 2,330 cases in the 1975-1980 period to only 122 cases in 1981. The last case of paralytic poliomyelitis caused by endemic transmission of wild poliovirus occurred in March 1989 in the northeast region of the country (5). …”

Path of infectious diseases in Brazil in the last 50 years: an ongoing challenge

“…Measles was considered the leading cause of death among children aged from one to four years in major cities from different regions of Country 137 . Poliomyelitis was epidemic, leaving many individuals with motor sequelae, often aggravated by late manifestations (post polio syndrome) that worsen the quality of life 46 , 152 .…”