We can divide the philosophy of science into two projects. Let's call the first philosophydirected. Here, we seek to describe, systematize and explain scientific practice, and draw on this to argue for philosophical positions. Science informs philosophy. 2 The second could be named science-directed. We aim to clarify, clean-up and unify scientific concepts. Philosophy informs science 3. Both projects lean on generalizations about scientific method, practice, development and so on. Frequently, such generalizations are made in reference to case studies, particular, detailed descriptions of scientific activity. Here, I defend the use of case studies in both philosophy-directed and science-directed contexts. My defence is pluralistic: case studies play a variety of roles in philosophical methodology, and particular case studies act in more than one. These roles fall into three categories. First, we take case studies as inductive evidence. As we shall see, due to the heterogeneity of scientific practice, this can lead to a 'natural history' of science: philosophers ought to restrict themselves to detailed studies of particular scientific practices and refuse to posit generalizations. I resist both that science is so heterogeneous, and that philosophy of science need be so particularist. Second, case studies play a non-justificatory, pragmatic or perhaps rhetorical role. For example, referring to the same case study can centre dispute, providing philosophers common ground. I argue that overemphasizing the heuristic use of case studies can undermine them. The third 1 An early version of this paper was presented at PBDB7. Drafts were read by Marc Ereshefsky, Kirsten Walsh, Brandon Holter, Chris Daly and Alex Prescott-Couch. Their feedback is greatly appreciated. 2 Alex Prescott-Couch has suggested to me that philosophy-directed projects be divided again: one project aims to explain scientific practice, where the other draws on science to inform philosophical debate. 3 Godfrey-Smith (2009) makes a similar distinction, naming the 'science-directed' philosophy 'philosophy of nature'. 2. The Curse Here's a paper-schema philosophers will be familiar with. First, introduce some philosophical issue; second, launch into a detailed description some scientific endeavour; third, draw some general lessons on the original issue. In essence, I'm going to argue in support of that strategy. Why does it need support? Because prima facie, there's something problematic about how philosophers of science use case studies. At least one of our tasks is to generalize across scientific practice, and case studies don't help. The 'curse of the case study', then, is that case studies, by their nature, are peculiar and individual, but the generalizations philosophers seek are broad and unitary. On the face of it, we should switch our aims to suit our evidence, or switch our methodology to suit our aims. I'll start by providing some examples of the practice, before describing the problem. Note that I will be drawing on examples of philosophy-directed...