2012
DOI: 10.1590/s0104-11692012000300010
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Abstract: This study identified the prevalence and predictors of fatigue in colorectal cancer (CRC) patients.Cross-sectional study with 157 adult CRC outpatients (age 60±11.7 years; 54% male; cancer stage IV 44.8%). The Piper Fatigue Scale-revised was used to assess fatigue scores. Socio-demographic, clinical, depression, performance status, pain and sleep disturbance data were assessed. Associations between fatigue and these data were analyzed through logistic regression models. Fatigue was reported by 26.8% patients. … Show more

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Cited by 40 publications
(29 citation statements)
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References 25 publications
(38 reference statements)
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“…An alteration of muscle fiber innervation contributes to explaining the functional deficit observed in cachectic muscles. It is well known that cachectic mice and men have lower muscle performance and a high prevalence of fatigue [53,54]. Similar functional deficits are reported in sarcopenia: focal denervation accounting for local switches to a slow fiber phenotype, severe atrophy of certain muscle fibers, and diminished muscle force [55].…”
Section: Discussionmentioning
confidence: 76%
“…An alteration of muscle fiber innervation contributes to explaining the functional deficit observed in cachectic muscles. It is well known that cachectic mice and men have lower muscle performance and a high prevalence of fatigue [53,54]. Similar functional deficits are reported in sarcopenia: focal denervation accounting for local switches to a slow fiber phenotype, severe atrophy of certain muscle fibers, and diminished muscle force [55].…”
Section: Discussionmentioning
confidence: 76%
“…Sleep problems are prevalent in cancer patients [5], nearly two-thirds of patients reported symptoms including long latency periods before falling or staying asleep, frequent nocturnal awakenings, and impaired seep quality [6]. Higher levels of sleep problems predicted for more fatigue, depression and poorer performance status [7].…”
Section: Introductionmentioning
confidence: 99%
“…Many factors exacerbate the symptoms of fatigue in patients. On the basis of the severity of the disease, fatigue-related factors can be associated with very broad aspects such as the socioeconomic factors (gender, level of education, having a permanent job) or the clinical characteristics of the disease (duration of diagnosis, diet therapy, the physical condition of the patient, and the type of cancer) and each can affect the level of fatigue in the patient (14). Although the possible roles of some variables such as the stage of disease, the type of cancer, and anaemia have been reported in cancerrelated fatigue, there is insufficient evidence yet.…”
Section: Introductionmentioning
confidence: 99%