Heterogeneity of linalool chemotypes of Lippia alba (Mill.) N.E.Br., based on clonal half-sib progenies

Bottignon, Marcos Ribeiro; Rufino, Elcio Rodrigo; Marques, Márcia Ortiz Mayo; Colombo, Carlos Augusto; Filho, Joaquim Adelino de Azevedo; Lourenção, André Luiz; Martins, Antonio Lúcio Mello; Siqueira, Walter José

doi:10.1590/s0103-90162011000400009

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…Data shown in Table 1 indicate that LA‐EO was obtained from an L. alba linalool chemotype. The EO composition of L. alba linalool chemotypes from other Brazil regions have also been reported [15] …”

Section: Resultsmentioning

confidence: 91%

Trypanocidal Activity of Dysphania ambrosioides, Lippia alba, and Tetradenia riparia Essential Oils against Trypanosoma cruzi

Crotti

Pagotti

Cândido

et al. 2021

Chemistry & Biodiversity

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Despite the current treatments against Chagas Disease (CD), this vector-borne parasitic disease remains a serious public health concern. In this study, we have explored the in vitro and/or in vivo trypanocidal and cytotoxic activities of the essential oils (EOs) obtained from Dysphania ambrosioides (L.) Mosyakin & Clemants (Amaranthaceae) (DA-EO), Lippia alba (Mill.) N.E. Brown (Verbenaceae) (LA-EO), and Tetradenia riparia (Hochst.) Codd (Lamiaceae) (TR-EO) grown in Brazil Southeast. DA-EO was the most active against the trypomastigote and amastigote forms in vitro; the IC 50 values were 8.7 and 12.2 μg mL À 1 , respectively. The EOs displayed moderate toxicity against LLCMK2 cells, but the DA-EO showed high selectivity index (SI) for trypomastigote (SI = 33.2) and amastigote (SI = 11.7) forms. Treatment with 20 mg/kg DA-EO, LA-EO, or TR-EO for 20 days by intraperitoneal administration reduced parasitemia by 6.36 %, 4.74 %, and 32.68 % on day 7 and by 12.04 %, 27.96 %, and 65.5 % on day 9. These results indicated that DA-EO, LA-EO, and TR-EO have promising trypanocidal potential in vitro, whereas TR-EO has also potential trypanocidal effects in vivo.

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Section: Resultsmentioning

confidence: 91%

Trypanocidal Activity of Dysphania ambrosioides, Lippia alba, and Tetradenia riparia Essential Oils against Trypanosoma cruzi

Crotti

Pagotti

Cândido

et al. 2021

Chemistry & Biodiversity

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Herbal buccal films with in vitro antibacterial and anti-inflammatory effects

Zamora

Michaluk

Núñez

2022

Journal of Herbal Medicine

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Flower-Visiting Insects and Phenology ofLippia alba(Lamiales: Verbenaceae): Floral Color Changes and Environmental Conditions as Cues for Pollinators

Venâncio¹,

Viccini²,

Luizi-Ponzo³

et al. 2016

Environ Entomol

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Lippia alba (Mill.) N.E. Br. ex Britton & P. Wilson (Verbenaceae) is a herbal aromatic shrub with medicinal properties. Natural populations of this species are allogamous and self-incompatible. Therefore, this plant species relies on pollinators to outcross and maintain the genetic variability. Here, we investigated the floral phenology, pollen morphology, the floral visitor entomofauna, and the influence of climatic factors on the frequency of visits in L. alba flowers. The study was conducted at Federal University of Juiz de Fora Plant Experimental Area, southeast Brazil. The flowering of L. alba occurred throughout the whole year. The anthesis is diurnal and lasts 5 d. The nectar guide was visible from the onset of flowering until the third day. Pollen grains were classified as isopolar, oblate spheroidal, three-colporate (rare, four-colporate), surface tectate-perforate, and endoaperture lalongate, with median constriction. Insects from the order Hymenoptera were the most frequent visitors observed, followed by Lepidoptera, Thysanoptera, Diptera, and Hemiptera-Heteroptera. The preference of insects for flowers with nectar guides shows that the color is likely to be an important visual trait to increase the frequency of visits. Moreover, the climate variables temperature, relative humidity, wind speed, and light were important to define the composition of the most frequent floral visitors.

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Heterogeneity of linalool chemotypes of Lippia alba (Mill.) N.E.Br., based on clonal half-sib progenies

Cited by 3 publications

References 10 publications

Trypanocidal Activity of Dysphania ambrosioides, Lippia alba, and Tetradenia riparia Essential Oils against Trypanosoma cruzi

Trypanocidal Activity of Dysphania ambrosioides, Lippia alba, and Tetradenia riparia Essential Oils against Trypanosoma cruzi

Herbal buccal films with in vitro antibacterial and anti-inflammatory effects

Flower-Visiting Insects and Phenology ofLippia alba(Lamiales: Verbenaceae): Floral Color Changes and Environmental Conditions as Cues for Pollinators

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