Vaginal leiomyosarcoma in a cow from Uberlândia, Minas Gerais, Brazil

Saut, João Paulo Elsen; Oliveira, Patrícia Magalhães de; Nasciutti, Nayara Resende; Medeiros, Alessandra Aparecida; Magalhães, Geórgia Modé; Tsuruta, Suzana Akemi; Hanna, Paul E.; Headley, Selwyn Arlington

doi:10.1590/s0103-84782013005000049

Cited by 5 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Leiomiossarcoma é uma neoplasia maligna de músculo liso, não muito frequente em bovinos, porém, já foi relatada no útero (TESSELE et al, 2016), e na vagina (SAUT et al, 2013). No presente estudo, a neoplasia foi diagnosticada em um bovino que estava clinicamente apático e anoréxico, sendo que na avaliação post mortem dos pré-estômagos e estômago, observou-se nódulo infiltrativo de 15X10 cm, consistência firme, de coloração esbranquiçada ao corte, aderindo a serosa do rúmen ao abomaso.…”

Section: Resultsunclassified

Untitled

2017

BDPatVet

View full text Add to dashboard Cite

Em 2016, primeiro ano de publicação de resultados em forma de boletim, o Laboratório de Patologia Veterinária do IFC-Concórdia apresenta as principais enfermidades diagnosticadas que acometem os animais de produção na região do Alto Uruguai Catarinense. O objetivo é auxiliar os veterinários de campo em seus trabalhos na propriedade rural, disponibilizando a casuística dos diagnósticos nos animais de produção detectada pelo laboratório. Ainda, instigar os acadêmicos do curso de Medicina Veterinária para a realidade das necropsias a campo e do importante serviço de extensão que isso significa à região.

show abstract

Section: Resultsunclassified

Untitled

2017

BDPatVet

View full text Add to dashboard Cite

show abstract

“…Neoplasias no trato genital causam prejuízos à criação de bovinos pelas perdas reprodutivas e também pelo descarte desses animais [21]. Os principais tumores já diagnosticados afetando a vagina de vacas são aqueles originários de tecido conectivo -fibromas, fibropapilomas e fibrossarcomas -e de tecido muscular -leiomioma e leiomiossarcoma [6,8,10,15,16,21]. Em vacas que desenvolvem a forma multicêntrica da leucose bovina, células neoplásicas podem estar presentes no útero [7,11] formando nódulos ou massas, e menos frequentemente na vagina [11].…”

Section: Discussionunclassified

Hemolytic Crisis in a Dog with Copper-Associated Chronic Hepatitis

Mazaro

Luz

Herbichi

et al. 2019

Acta Scientiae. Vet.

View full text Add to dashboard Cite

Background: Skin tumors are the most common neoplasia in veterinary medicine and squamous cell carcinoma (SCC) is the most frequent. In cattle, it is the main tumor besides linfosarcoma and normally affects taurine cattle, but is rare in Nelore cattle. SCC mainly affects mucocutaneous junctions such as the eyelids, sclera, vulva, and perineum, and has already been described in vagina, eye, and periocular tissues, in addition to the superior digestive tract. The purpose of this paper is to describe a vaginal squamous cell carcinoma in a Nelore cow. Case: A 10-year-old Nelore cow, used as an embryo donor, was submitted to a necropsy procedure. Clinically, the animal had prolonged recumbency, anorexia, weight loss, and vaginal discharge. There was a history of recurrent vaginal prolapses and an intraluminal vaginal mass that had grown over two years. At necropsy, there was diffuse fibrinous peritonitis with marked intestinal adhesions; the vagina was markedly expanded and measured 40 × 20 cm due to the presence of an intraluminal mass occupying the vestibulum and extending up to the cervix. In the vaginal lumen, there was large amount of fibrinonecrotizing malodorous material; the vaginal wall was thickened by an unencapsulated and poorly delimited, firm and white mass composed of sheets and nests of epithelial cells from the squamous layer surrounded by abundant fibrovascular stroma. The neoplastic cells were polygonal with marked pleomorphism, anisokaryosis, and anisocytosis; abundant eosinophilic and well-defined cytoplasmic borders. Sometimes it was possible to see desmosomes. The nuclei were rounded to oval with sparse chromatin and one or more nucleoli were seen. Mitotic figures were frequent (at least 3 per higher power field) and there were also a few multinucleated cells. Frequently, there was the formation of distinct keratin "pearls". Discussion: SCC frequently occurs in the skin, eyes, and vulva in cattle, since these are sites that lack pigment within the epidermis and have prolonged exposed to ultraviolet light. Vaginal SCC has already been described in one cow with recurrent vaginal prolapses that was submitted to follicular aspiration. In a survey of cattle tumors, most genital tract neoplasias affected the uterus, and vaginal tumors normally originated from connective tissue -fibromas, fibropapillomas, and fibrosarcoma -or muscular tissue -leiomyoma and leiomyosarcoma. Irreversible changes in cellular DNA can occur due to physical or chemical carcinogens, and also chronic inflammation. The cow in this paper was frequently submitted to follicular aspiration and this can cause chronic inflammation in the vaginal mucosa after the puncture and, when it's chronic, can represent one of the main initiating factors for tumor development. This cow's death was caused by diffuse and marked peritonitis. The same cause was previously described in cows submitted to follicular aspiration and, in one of these animals, there was a rectal perforation caused by mistakes during the procedure. In this animal, we did not...

show abstract

“…In the veterinary literature, soft tissue fibrous tumors are divided into few types, and in cattle the majority are diagnosed as fibroma or fibrosarcoma (McEntee and Nielsen 1976;Takai et al, 2004;Michishita et al, 2016;Mohana et al, 2016). Vaginal tumors in cattle have been reported from many countries (Saut et al, 2013;Kuru et al, 2016), however, reports on bovine fibrosarcoma compared with other tumors of cattle are very rare (Yeruham et al, 1999;Musal et al, 2007). Vagina tumors may be associated with dystocia (Arthur, 1996); also, temporal infertility might occur in cases of a very large neoplasm, due to vaginal obstruction and/or inability to successfully breed.…”

Section: Introductionmentioning

confidence: 99%

Vaginal Fibrosarcoma in an Algerian Crossbreed Cow

Hemida¹

2018

PVJ

View full text Add to dashboard Cite

A case of vaginal fibrosarcoma in a 4-year-old pregnant (6th month) cow is described on the basis of clinical, macroscopic and microscopic findings. Tumor mass surgically excised from the vagina was nodular and firm, sized 40mm x 60mm. Histopathologically, neoplastic tissue originated from the mucosal connective tissue. Tumor cells showed highly proliferating pattern with cellular and nuclear pleomorphism (anisocytosis and anisokaryosis). In addition, some tissue parts were very well vascularized. Excision of the tumor mass was easy and successful; with neither hemorrhage nor postoperative infection. At the 5 th post surgical month, no evidence of regrowth of any tumor tissue was found. This paper reports the first clinical investigation, surgical treatment and pathological description of a vaginal fibrosarcoma in Algeria.

show abstract

Vaginal leiomyosarcoma in a cow from Uberlândia, Minas Gerais, Brazil

Abstract: The clinical, pathological, and immunohistochemical fi ndings associated with a vaginal leiomyosarcoma in a 12-year-

Cited by 5 publications

References 7 publications

Untitled

Untitled

Hemolytic Crisis in a Dog with Copper-Associated Chronic Hepatitis

Vaginal Fibrosarcoma in an Algerian Crossbreed Cow

Contact Info

Product

Resources

About