Eficácia de vermífugos à base de avermectinas e milbemicinas utilizados há cinco anos em uma criação de eqüinos

Nogueira, Carlos Eduardo Wayne; Lima, Alzira Pacheco de; Ruas, Jerônimo Lopes; Jardim, Alexandre de Leon

doi:10.1590/s0103-84782002000400026

Cited by 2 publications

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References 4 publications

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“…Although there have been reports of anthelmintic resistance against this active ingredient (BOERSEMA et al, 2002), the results of the present study in naturally infected equines showed the efficacy of ivermectin for helminth infection reduction in horses using EPG count, as reported by other authors (NOGUEIRA et al, 2002;ARAÚJO et al, 2008;SARTORI FILHO et al, 1993;PICHÉ et al, 1991;TAYLOR;KENNY, 1995;CAMPOS PEREIRA et al, 1991). It can be thus confirmed that ivermectin is still a good alternative in equine health programs once the susceptible populations are identified in a horse herd.…”

supporting

confidence: 78%

Field study on the efficacy of an oral 2% ivermectin formulation in horses

Cutolo

Santos

Allegretti

2011

Rev. Bras. Parasitol. Vet.

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Twenty horses naturally infected with nematodes were included in a blind, controlled field study on efficacy and safety of an oral 2% ivermectin formulation at a dose of 0.2 mg.kg -1 . Horses were divided into treated and non-treated (control) groups with ten animals each based on preliminary counts of eggs per gram of feces (EPG). Stool samples were collected after treatment for identification of nematode species. Clinical evaluations and EPG counts were performed on days 0, +5, +14 and +19. Days -15, 0, +5, +14 and +19 were 1925Days -15, 0, +5, +14 and +19 were , 1340Days -15, 0, +5, +14 and +19 were , 0, 12.5, 0, 1470Days -15, 0, +5, +14 and +19 were , 790, 875, 1605Days -15, 0, +5, +14 and +19 were and 1240 respectively. The efficacy of treatment on Days +5, +14 and +19 was 100, 99.2 and 100% respectively, with a significant difference compared to the control group (p < 0.01). The product was considered to be safe with no findings of clinical significant changes during the study.Keywords: Anthelmintic, EPG, efficacy, dewormer, antiparasitic. ResumoVinte equinos naturalmente infectados com nematódeos foram utilizados em estudo cego, controlado, de eficácia e segurança clínica a campo de uma formulação oral de ivermectina a 2%, na dosagem de 0,2 mg.kg -1 . Foram distribuídos em grupos: tratado e sem tratamento, de dez animais cada, baseados na contagem prévia de ovos por grama de fezes (OPG). Amostras de fezes foram colhidas pós-tratamento para identificação da helmintofauna. Avaliações clínicas e OPG foram realizados nos dias 0, +5, +14 e +19. Identificou-se dezenove espécies de nematódeos: Coronocyclus ulambajari, Craterostomum acuticaudatum, Cyathostomum catinatum, Cyathostomum pateratum, Cylicocyclus brevicapsulatus, Cylicocyclus insigne, Cylicocyclus leptostomum, Cylicocyclus nassatus, Cylicocyclus ultrajectinus, Cylicocyclus spp., Cylicostephanus calicatus, Cylicostephanus longibursatus, Cylicostephanus poculatus, Habronema muscae, Habronema spp., Parascaris equorum, Poteriostomum imparidentatum, Oxyuris equi e Triodontophorus spp.. As contagens médias de OPG dos grupos tratado e controle nos dias -15, 0, +5, +14 e +19 foram respectivamente 1925, 1340, 0, 12,5, 0 e 1470, 790, 875, 1605 e 1240. A eficácia do produto nos dias +5, +14 e +19 foi respectivamente de 100, 99,2 e 100%, com diferença significativa em relação ao grupo controle (p < 0,01). O produto mostrou-se seguro, não sendo observadas alterações clínicas dignas de nota durante o experimento.Palavras-chave: Anti-helmíntico, OPG, eficácia, equino, vermífugo.

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supporting

confidence: 78%

Field study on the efficacy of an oral 2% ivermectin formulation in horses

Cutolo

Santos

Allegretti

2011

Rev. Bras. Parasitol. Vet.

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“…Among the drugs used to control parasites in horses, moxidectin is the only one with some action against encysted cyathostomins, and is recommended for the control of this group of nematodes. A high effectiveness index is reported for this drug (Nogueira et al, 2002;Traversa et al, 2007). However, reduced efficacy of moxidectin (MOX) against cyathostomins has also been described in Brazil (Molento et al, 2008).…”

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confidence: 99%

Assessment of the efficacy of commercial anthelmintics in horses naturally infected with gastrointestinal nematodes

et al. 2021

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The objective of this study was to assess the efficacy of commercial anthelmintics in horses naturally infected with gastrointestinal nematodes from the southern Rio Grande do Sul state, Brazil. The anthelmintic efficacy was assessed by fecal egg count reduction test (FECRT) and coproculture. Fecal samples were collected from 110 animals in seven farms located in the southern region of the state of Rio Grande do Sul, in the south of Brazil. Criteria used to suspect anthelmintic resistance included percentages of efficacy lower than 95% and a lower limit of the confidence interval below 90%. Anthelmintic resistance was detected in five of the seven farms studied. Coproculture results show that, even after horses were treated with anthelmintics, infection by nematodes of the subfamily Cyathostominae was still present in animals from five farms.

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Eficácia de vermífugos à base de avermectinas e milbemicinas utilizados há cinco anos em uma criação de eqüinos

Cited by 2 publications

References 4 publications

Field study on the efficacy of an oral 2% ivermectin formulation in horses

Field study on the efficacy of an oral 2% ivermectin formulation in horses

Assessment of the efficacy of commercial anthelmintics in horses naturally infected with gastrointestinal nematodes

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