Densitometria óptica radiográfica na avaliação do hiperparatireoidismo secundário nutricional induzido em gatos jovens

Rahal, Sheila Canevese; Mortari, Ana Carolina; Caporali, Evelyn Hasegawa Gonçalves; Vulcano, Luiz Carlos; Santos, Flávio Augusto Marques dos; Takahira, Regina Kiomi; Crocci, Adalberto José

doi:10.1590/s0103-84782002000300009

Cited by 16 publications

(25 citation statements)

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“…This technique had already been well described in rabbits 18 , rats 19 , cats 20 , equines 21 and humans 22 , among other species. To minimize the possibility of radiographic standardization errors, an 11-step ultra-purified aluminum…”

Section: ■ Discussionmentioning

confidence: 98%

Allogeneic mesenchymal stem cells and xenogenic platelet rich plasma, associated or not, in the repair of bone failures in rabbits with secondary osteoporosis

et al. 2017

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Allogeneic mesenchymal stem cells and xenogenic platelet rich plasma, associated or not, in the repair of bone failures in rabbits with secondary osteoporosis¹ 9-Experimental SurgeryActa Cir Bras. 2017;32(9):767-780 AbstractPurpose: To assess the efficacy of allogeneic mesenchymal stem cells and xenogenic platelet rich plasma in the treatment of bone failure of osteoporotic rabbits secondary to estrogenic deprivation and iatrogenic hypercortisolism. Methods: Eight female rabbits underwent ovarian resection and corticoid therapy to induce clinical status of osteoporosis. Four failures were produced in the tibiae, with each failure being treated with hemostatic sponge, allogenic mesenchymal stem cells, xenogenic plateletrich plasma and the association between both. The animals were divided into two groups, evaluated radiographically and histopathologically at 30 and 60 days post treatment. Results: A radiographically confirmed consolidation of bone failures treated with allogeneic mesenchymal stem cells, associated with the histopathological image of mature and immature bone tissue, without evidence of osteopenia, was compared with the other groups, in which radiolucent failures with osteopenia and fibrosis were still present, denoting the satisfactory effect of the first treatment in detriment to the others. Conclusion:The treatment of bone failures of rabbits with secondary osteoporosis with allogeneic mesenchymal stem cells induced greater bone consolidation with mature and immature bone tissue production (p<0.01), when compared to the other treatments.

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Section: ■ Discussionmentioning

confidence: 98%

Allogeneic mesenchymal stem cells and xenogenic platelet rich plasma, associated or not, in the repair of bone failures in rabbits with secondary osteoporosis

et al. 2017

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“…A avaliação da densidade mineral óssea (DMO) da extremidade distal do rádio direito foi realizada pela técnica de densitometria óptica em imagens radiográficas por RAHAL et al 2002), em quatro momentos. Para melhor análise sequencial dos valores densitométricos, padronizou-se a seleção da região da metáfise localizada 5mm acima da epífise.…”

Section: Methodsunclassified

Marcadores do metabolismo ósseo em gatos

et al. 2010

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“…A avaliação da densidade mineral óssea foi realizada pela técnica de densitometria óptica em imagens radiográficas, conforme previamente descrito na literatura (Vulcano et al, 1998;Rahal et al, 2001;Vulcano, 2001). A área avaliada foi a extremidade distal do rádio direito e, para melhor análise seqüencial dos valores densitométricos, padronizou-se a seleção da região da metáfise localizada 5mm acima da cicatriz epifisária em todos os animais e em todos os momentos experimentais, sendo posteriormente feito o cálculo da densidade mineral óssea (Fig.…”

Section: Methodsunclassified

Avaliação das metaloproteinases de matriz -2 e -9 em gatos com desmineralização óssea secundária à tirotoxicose induzida

Costa¹,

Cardoso

Muniz

et al. 2008

Arq. Bras. Med. Vet. Zootec.

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Avaliação das metaloproteinases de matriz -2 e -9 em gatos com desmineralização óssea secundária à tirotoxicose induzida RESUMOObservou-se significativo aumento de atividade das formas ativas das metaloproteinases -2 e -9 em gatos com tirotoxicose induzida e desmineralização óssea. As formas pró e intermediária da metaloproteinase -2 elevaram-se com 14 dias de administração hormonal, porém, posteriormente, houve uma tendência de queda. Observou-se correlação negativa entre a forma ativa das metaloproteinases de matriz -2 e -9 e a densidade mineral óssea da extremidade distal do rádio. Os resultados sugerem aumento da degradação da matriz colágena secundária com a elevação dos hormônios tiroidianos.Palavras-chave: gato, hipertiroidismo, tirotoxicose, desmineralização óssea, metaloproteinase de matriz ABSTRACTSignificant increase of activity of active forms of matrix metalloproteinases -2 and -9 in cats under induced thyrotoxicosis and bone demineralization was observed. Pro and intermediated forms of matrix metalloproteinases -2 and -9 increased at 14 days of hormonal treatment, followed by decrease tendency. A negative correlation between active forms of matrix metalloproteinases -2 and -9 and bone mineral density of radius distal extremity was also observed. The results suggest an increase of collagen matrix degradation secondary to high levels of thyroid hormones.

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Densitometria óptica radiográfica na avaliação do hiperparatireoidismo secundário nutricional induzido em gatos jovens

Abstract: RESUMO

Cited by 16 publications

References 4 publications

Allogeneic mesenchymal stem cells and xenogenic platelet rich plasma, associated or not, in the repair of bone failures in rabbits with secondary osteoporosis

Allogeneic mesenchymal stem cells and xenogenic platelet rich plasma, associated or not, in the repair of bone failures in rabbits with secondary osteoporosis

Marcadores do metabolismo ósseo em gatos

Avaliação das metaloproteinases de matriz -2 e -9 em gatos com desmineralização óssea secundária à tirotoxicose induzida

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