Anestesia geral com propofol em cães pré-tratados com acepromazina e alfentanil

Cortopassi, Silvia Renata Gaído; Holzchuh, Marlene Pezzutti; Fantoni, Denise Tabacchi

doi:10.1590/s0103-84782000000400013

Cited by 2 publications

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References 33 publications

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“…Reduction in the mean arterial blood pressure was observed by Ferro et al (2005) and Cortopassi et al (2000), suggesting that depression was probably caused by propofol acting on vasomotor centers located in the brain stem, resulting in the combination of a reduced cardiac output and systemic vascular resistance, and possibly by the combination with other drugs (acepromazine in this case). Changes in blood pressure were not observed by Pereira et al (2013), by implementing doses of 0.3 mg kg -1 of methadone, intramuscularly and intravenously in dogs.…”

Section: Resultssupporting

confidence: 52%

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Cardiorespiratory and electrocardiographic effects of methadone or morphine in the perioperative period in anesthetized dogs with continuous rate infusion of propofol and submitted to ovariohysterectomy

Cintra

Duque

Silveira

et al. 2017

SCA

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Cardiorespiratory and electrocardiographic effects of methadone or morphine in the perioperative period in anesthetized dogs with continuous rate infusion of propofol and submitted to ovariohysterectomyEfeitos cardiorrespiratórios e eletrocardiográficos da metadona ou morfina no período perioperatório em cães anestesiados com infusão contínua de propofol e submetidos a ovário-histerectomia AbstractThe aims of this study were compare the electrocardiogram (ECG) and cardiopulmonary effects of methadone or morphine, both injected intravenously (IV) in dogs anesthetized with continuous infusion of propofol. Sixteen healthy female mongrel dogs were used in this study for elective ovariohysterectomy. The animals were allocated in random order into two groups assigned GME (methadone 0.3 mg kg -1 , IV) or GMO (morphine 0.3 mg kg -1 , IV). Parameters were evaluated: heart rate (HR), P-wave amplitude (Ps and PmV), interval between Ps and R waves (PR), QRS duration (QRS), R-wave amplitude (R), duration the interval between the Q and T waves (QT), systolic blood pressure (SBP), rectal temperature (RT), respiratory rate (RR), end tidal of carbon dioxide (ETCO 2 ) and periferic oxyhemoglobin saturation (SpO 2 ). Postoperative analgesia was assessed by mechanical nociceptive stimulus based on the scale proposed by Firth and Haldane (1999) and rescue analgesia based on the visual analogue scale. HR was lower in GME in relation to GMO. The P, PmV, PR, QRS, R and QT values remained within their normality tracks, showing no clinical importance. Apnea and ETCO 2 increased in both groups. There was no difference between groups of the analgesic effects. It can be concluded that methadone and morphine promote similar cardiovascular effects after IV injection during surgery in dogs anesthetized with propofol by continuous rate infusion, however, when methadone used, assisted ventilation is required. In addition, both drugs promote postoperative analgesia until six hours. ResumoO presente estudo teve como objetivo comparar as alterações no eletrocardiograma (ECG) e nos parâmetros cardiorrespiratórios da metadona ou morfina administrada pela via intravenosa (I.V.) em cães anestesiados com infusão intravenosa contínua de propofol. Foram utilizados 16 cadelas, sem raça definida submetidos ao procedimento de ovário-histerectomia. Os animais foram distribuídos aleatoriamente em dois grupos, designados como GME (metadona 0,3 mg kg -1 , I.V.) ou GMO (morfina 0,3 mg kg -1 , I.V.). Os parâmetros avaliados foram frequência cardíaca (FC), tempo e amplitude da onda P (Ps e PmV), intervalo entre as ondas P e R (PR), duração do complexo QRS (QRS), amplitude da onda R (R), duração do intervalo entre as ondas Q e T (QT), pressão arterial sistólica (PAS), temperatura retal (TR), frequência respiratória (f), tensão de dióxido de carbono no final da expiração (ETCO 2 ) e saturação de oxigênio na hemoglobina (SpO 2 ). A analgesia pós-operatória foi verificada seguindo a proposta de Firth e Haldane (1999) e o regaste analgésico baseado na escala análoga v...

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Section: Resultssupporting

confidence: 52%

“…Cortopassi et al (2000) found an increase in PaCO 2 due to alfentanil administration that remained higher after the application of propofol. Therefore, it can be presumed that the increase in ETCO 2 in this study may have been caused by the association of opioid drugs with the depressant effect of propofol on respiratory function.…”

Section: Resultsmentioning

confidence: 87%

Cardiorespiratory and electrocardiographic effects of methadone or morphine in the perioperative period in anesthetized dogs with continuous rate infusion of propofol and submitted to ovariohysterectomy

Cintra

Duque

Silveira

et al. 2017

SCA

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Avaliação de parâmetros hemostáticos em cães de diferentes categorias de risco anestésico no período peri-operatório

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Anestesia geral com propofol em cães pré-tratados com acepromazina e alfentanil

Abstract: RESUMO Foram utilizados 30 cães, sem raça definida, adultos, (10 machos e 20 fêmeas), com peso médio de 14,44 ± 2,72kg, distribuídos em três grupos. O grupo I (GI) recebeu

Cited by 2 publications

References 33 publications

Cardiorespiratory and electrocardiographic effects of methadone or morphine in the perioperative period in anesthetized dogs with continuous rate infusion of propofol and submitted to ovariohysterectomy

Cardiorespiratory and electrocardiographic effects of methadone or morphine in the perioperative period in anesthetized dogs with continuous rate infusion of propofol and submitted to ovariohysterectomy

Avaliação de parâmetros hemostáticos em cães de diferentes categorias de risco anestésico no período peri-operatório

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