2010
DOI: 10.1590/s0103-50532010000600002
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Abstract: As propriedades da prata são conhecidas há muitos anos. Recentemente, as nanopartículas de prata têm chamado a atenção por sua atividade antimicrobiana que oferece a possibilidade de uso com propósitos médicos e de higiene. Estas nanopartículas de prata em diferentes formulações, com diferentes formas e tamanhos, exibem atividades antimicrobianas diferentes. Entretanto, os mecanismos da atividade antimicrobiana de íons e de nanopartículas, assim como sua toxicidade em tecidos humanos não estão totalmente escla… Show more

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Cited by 394 publications
(227 citation statements)
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“…: applying the so-called combined therapy, which uses two or more antibiotics administered simultaneously or combines the action of two different drugs in one molecule [8]. A promising alternative is the combination of chemotherapeutics with heavy metal ions, for example: silver, which has been known for its bactericidal properties since ancient times [9,10]. The ideal situation would be to use silver compounds to increase the antibacterial effectiveness of commonly known and used antibiotics.…”
Section: Introductionmentioning
confidence: 99%
“…: applying the so-called combined therapy, which uses two or more antibiotics administered simultaneously or combines the action of two different drugs in one molecule [8]. A promising alternative is the combination of chemotherapeutics with heavy metal ions, for example: silver, which has been known for its bactericidal properties since ancient times [9,10]. The ideal situation would be to use silver compounds to increase the antibacterial effectiveness of commonly known and used antibiotics.…”
Section: Introductionmentioning
confidence: 99%
“…A further eight review articles in scientific journals followed in 2010 [11][12][13][14][15][16][17][18] , plus substantial reports commissioned by the Environmental Protection Agency (EPA) in the US (which ran to 221 pages) 19 and the Joint Research Centre (JRC) of the European Commission (426 pages) 20 . Two of the review articles in journals were also funded by the European Commission 14,16 .…”
mentioning
confidence: 99%
“…Because there have been very few original studies of the relationship between nanosilver and the development of antimicrobial resistance (less than five to the best of our knowledge), it is likely that the SCENIHR will rely heavily on the seven review articles that have addressed this topic 3,7,10,15,17,19,25 . Evidence that the increasing use of nanosilver may be leading to bacterial and fungal resistance towards silver include reports of resistance to silver-based burn dressings (originally published in the mid-1970s and reviewed Many of these reviews and reports go through the same literature, cover the same ground and identify many of the same data gaps and research needs.…”
mentioning
confidence: 99%
“…One important nanostructure is the silver nanoparticles (Ag 0 ) or also nanoparticles of the silver cloride (AgCl). The silver nanoparticles biogenically synthesized are widely studied by many research groups in the world [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] and Ag 0 nanoparticles were quite efficient against Aedes aegypti.…”
Section: Introductionmentioning
confidence: 99%