2016
DOI: 10.1590/s0102-865020160010000008
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Abstract: PURPOSE:To evaluate the effects of particulate (granule-shaped) SCB on bone repair relating it to its biocompatibility and bone neoformation. METHODS:Thirty Wistar rats were submitted to a one 7-mm-diameter defect and divided equally into three experimental groups, with two different postoperative times of evaluation, 90 and 120 days. Each calvaria defect was filled up with clot (control group), particulated autogenous bone or granulated SCB. Five animals of each group were assessed at 90 and 120 days after su… Show more

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Cited by 8 publications
(9 citation statements)
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“…The BCG implants were remodeled and remained at the point of implantation in the anorectal region demonstrating biocompatibility with potential to be an efficient volume agent for the treatment of fecal incontinence. These results are similar to those found in other studies that studied cytotoxicity, biocompatibility and remodeling activity of bacterial cellulose [18, 28, 29].…”
Section: Discussionsupporting
confidence: 91%
“…The BCG implants were remodeled and remained at the point of implantation in the anorectal region demonstrating biocompatibility with potential to be an efficient volume agent for the treatment of fecal incontinence. These results are similar to those found in other studies that studied cytotoxicity, biocompatibility and remodeling activity of bacterial cellulose [18, 28, 29].…”
Section: Discussionsupporting
confidence: 91%
“…BCF becomes incorporated into the damaged biliary tissue with an accompanying chronic inflammatory reaction of variable degree. 14,16,17,29,30 Complete absorption of BCF has also been observed 12 weeks after implantation in the tympanic bulla of Wistar rats, and when used to replace, dura mater is gradually absorbed over a period of three months, perhaps owing to use of a thinner film. 31 Similar findings have been reported for extrahepatic ductal grafts composed of a bioabsorbable tube of polylactic acid polymer and polycaprolactone which are completely absorbed by the fourth month.…”
Section: Discussionmentioning
confidence: 99%
“…Although relative ease of bio-integration and re-modelling has been documented, there are no reports in the literature on use of these biomaterials for repair of bile duct injuries. 14,[16][17][18] Against this background, use of bacterial cellulose membrane for repair of injuries to the extrahepatic biliary ducts represents a promising and potentially cost-effective treatment alternative (note use of these materials for urological procedures). Hence low levels of toxicity for bacterial cellulose coupled with its biocompatibility and proven benefit in experimental models have encouraged its use as a graft material to repair more complex and surgically challenging defects of the bile ducts.…”
Section: Introductionmentioning
confidence: 99%
“…Desta forma, promover a adesão de células a um biomaterial pode ajudar na integraçaõ do tecido conectivo mole com o implante, repercutindo no desenvolvimento de novas ferramentas (CARVALHO et al, 2010;MAGER et al, 2011;PIRES et al, 2015). Os biopolímeros despontam como biomateriais inovadores, em função da sua biocompatibilidade e o biopolímero de cana-deaçúcar (BCA), um exopolissacarídeo produzido a partir da fermentação do melaço pela bactéria Zoogloea sp., vem sendo utilizado em diversas aplicações nas áreas das Ciências da Saúde e da Biologia (PATERSON-BEEDLE et al, 2000;CASTRO, et al, 2004;AGUIAR et al, 2007;CAVALCANTE, et al, 2007;SILVEIRA et al, 2007;MAYER et al, 2011;MARTINS et al, 2013;SILVEIRA et al, 2014;ABREU et al, 2016). Em função do exposto, objetivamos avaliar in vitro o processo de adesão de macrófagos J774 com arcabouços 3D a base de biopolímero de cana-de-açúcar.…”
Section: Introductionunclassified