2015
DOI: 10.1590/s0102-865020150040000002
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Abstract: PURPOSE:To evaluate the anti-inflammatory and analgesic effects of green tea (Camellia sinensis) in mice. METHODS:The anti-inflammatory effect of alcoholic extracts of green tea (AE) was evaluated in a cell migration assay with four groups of six Swiss mice receiving 0.07g/Kg or 0.14g/Kg EA (treatment groups), saline (negative control) or 10mg/Kg indomethacin (positive control) by gavage. One hour later 300 µg carrageen an was administered intraperitoneally or subcutaneously. The analgesic effect was evaluated… Show more

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Cited by 16 publications
(15 citation statements)
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“…Syarayah reports that EGCG as an antioxidant works by lowering the phosphorylation of IkB to block the IL-1β that is induced by the activation of NF-kB. Mota reports that 140 mg/kg of EGCG shows a decrease of the expansion of cell inflammation in the mice that have been induced with inflammation [18]. …”
Section: -4mentioning
confidence: 99%
“…Syarayah reports that EGCG as an antioxidant works by lowering the phosphorylation of IkB to block the IL-1β that is induced by the activation of NF-kB. Mota reports that 140 mg/kg of EGCG shows a decrease of the expansion of cell inflammation in the mice that have been induced with inflammation [18]. …”
Section: -4mentioning
confidence: 99%
“…They are comprised on epigallocatechin gallate (23.4-112.4 lg/ml) as the major component, followed by epigallocatechin (18.4-78.9 lg/ml), epicatechin gallate (5.6-29.6 lg/ml), epicatechin (4.6-14.5 lg/ml) and catechin (3.2-8.2 lg/ml) [11]. The catechins effectively scavenge oxy-radicals involved in the pathogenesis of many chronic diseases, including cardiovascular diseases, cancer, neurodegenerative diseases, and ageing [12], antioxidant and prebiotic activities [13], anticancer [8], antidiabetic [14], antiinflammatory and analgesic effect [15].…”
Section: Introductionmentioning
confidence: 99%
“…Polyphenols are a group of secondary metabolites widely found in different plant organs such as fruits and leaves and their related processing products. Many studies have demonstrated that daily consumption of polyphenols-rich beverages and food such as green tea and olive oil is associated with a low incidence of several diseases including cancer, diabetes, obesity, leukemia, Parkinson's and cardiovascular diseases (Visioli et al, 2002;Mota et al, 2015). The beneficial health properties of green tea and olive oil consumption are related mainly to EGCG and HTyr, respectively, two phenolic compounds characterized by a wide range of biological activities (Visioli et al, 2002;Mota et al, 2015).…”
Section: Introductionmentioning
confidence: 99%
“…Many studies have demonstrated that daily consumption of polyphenols-rich beverages and food such as green tea and olive oil is associated with a low incidence of several diseases including cancer, diabetes, obesity, leukemia, Parkinson's and cardiovascular diseases (Visioli et al, 2002;Mota et al, 2015). The beneficial health properties of green tea and olive oil consumption are related mainly to EGCG and HTyr, respectively, two phenolic compounds characterized by a wide range of biological activities (Visioli et al, 2002;Mota et al, 2015). (-)-Epigallocatechin-3-gallate is the most abundant catechin phenolic compound found in Camellia sinensis L. leaves; and it is chemically characterized by the presence of two pyrogallol moieties ( Figure S1).…”
Section: Introductionmentioning
confidence: 99%
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