Micro-endoscopic ear anatomy of guinea pig applied to experimental surgery

Abstract

PURPOSE:To describe topographic and endoscopic anatomy of guinea pig ear for development of surgical approaches in experimental studies. METHODS:Experimental study. Eight adult guinea pigs (Cavia porcellus) were used in this study. Four animals were described through endoscopic view and four animals were used to describe topographic anatomy. RESULTS:The main structures of middle ear were well identified through endoscopy view: oval and round window, ossicles and vascular structures. Temporal bone position, landmarks and its relations to skull are perceived with topographic description. CONCLUSION:Topographic anatomic description allowed exposition of temporal bone relations for external surgical approaches.Alternatively, grooves and middle ear structures were identified and may be used to transcanal accesses.

Isolation, Characterization and Growth Kinetic Comparison of Bone Marrow and Adipose Tissue Mesenchymal Stem Cells of Guinea Pig

“…MSCs derived from Guinea pig as an animal model which has several parallels with the human condition can be used in auditory, immune system, skin and joint disease studies. Anatomy of the Guinea pig ear is important for inner ear studies ( 16 ). Similar immune system to human, similar antigen-macrophage interaction and delayed cutaneous hypersensitivity reaction ( 17 ) initiation and osteoarthritis progression in Guinea pig which develops spontaneously with advancing age are similar to human ( 18 ).…”

Correlation between computed tomography, magnetic resonance imaging and cross‐sectional anatomy of the head of the guinea pig (Cavia porcellus, Linnaeus 1758)

“…The guinea pig shares several reproductive characteristics with humans; therefore, it is extensively used in studying reproductive physiology, developmental studies and reproductive toxicological studies (Rocca & Wehner, 2009; Taylor & Lee, 2012). In addition, guinea pigs are commonly used in ontological research due to the anatomical similarities between guinea pigs and humans (Barros et al, 2014).…”

“…guinea pigs are commonly used in ontological research due to the anatomical similarities between guinea pigs and humans (Barros et al, 2014).…”