2014
DOI: 10.1590/s0102-86502014000700004
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Abstract: PURPOSE:To evaluate the healing of skin wounds induced experimentally in rats using a crystalline cellulose membrane (Veloderm ® ). METHODS:Thirty-two rats were divided into two groups: control group (CG) wounds treated with a solution of 0.9% sodium chloride and Veloderm ® group (VG) wounds treated with a crystalline cellulose membrane. The rats were evaluated at different times over twenty-six days. RESULTS:Weight loss was observed in the animals from both groups in the early stages, with greater weight in t… Show more

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Cited by 5 publications
(6 citation statements)
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“…However, several opposing results in the investigations of wound closure have been recently reported. Specifically, the percentage of wound contraction was lower in crystalline CM-treated Wistar rats than the 0.9% sodium chloride-treated group (10). Therefore, we hypothesized that these differences in wound repair may be caused by differences in the manufacturing process or additives, even though cellulose was used as a basic building material.…”
Section: Discussionmentioning
confidence: 99%
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“…However, several opposing results in the investigations of wound closure have been recently reported. Specifically, the percentage of wound contraction was lower in crystalline CM-treated Wistar rats than the 0.9% sodium chloride-treated group (10). Therefore, we hypothesized that these differences in wound repair may be caused by differences in the manufacturing process or additives, even though cellulose was used as a basic building material.…”
Section: Discussionmentioning
confidence: 99%
“…Surgical wounds treated with ORC have been shown to have a significantly lower number of infiltrated inflammatory cells when compared with the control group at 5 days post-surgery (35). In addition, a decrease in the infiltration of mononuclear cells was measured in skin wounds treated with crystalline CM at days 14, 21 and 26, even though a constant level was maintained until day 7 (10). In the present study, the number of inflammatory cells and mast cells markedly decreased in the FSCT-CM-treated group at days 7 and 14, while a decrease in the number of mast cells was detected in the SCT-CM treated group at day 14.…”
Section: Discussionmentioning
confidence: 99%
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“…A similar study conducted by other researchers reveals that the cellulose membrane is effective in the treatment of wounds in rats, is simple to use, protects and maintains wound humidity, and facilitates visualization and control of the lesion's progression. 66…”
Section: Discussionmentioning
confidence: 99%