Experimental models of human pathology are useful guides to new approaches
towards improving clinical and surgical treatments. A systematic search through
PubMed using the syntax (shock) AND (trauma) AND (animal model) AND
(cardiovascular) AND ("2010/01/01"[PDat]:
"2015/12/31"[PDat]) found 88 articles, which were reduced by
manual inspection to 43 entries. These were divided into themes and each theme
is subsequently narrated and discussed conjointly. Taken together, these
articles indicate that valuable information has been developed over the past 5
years concerning endothelial stability, mesenteric lymph, vascular reactivity,
traumatic injuries, burn and sepsis. A surviving interest in hypertonic saline
resuscitation still exists.