Abstract:PURPOSE:To evaluate the relationship between microvascular density and the expression of vascular endothelial growth factor (VEGF) and KIT as possible markers of angiogenic stimulus in astrocytic tumors and correlate it with histopathological grading.
METHODS:We enrolled 99 surgical specimens of supratentorial astrocytic tumors for analysis of VEGF and KIT and subsequent correlation with MVD and grading.
RESULTS:KIT and VEGF expression correlated with microvascular density (p<0.005) and both VEGF and microvasc… Show more
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