2012
DOI: 10.1590/s0102-86502012001200007
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Abstract: PURPOSES: To evaluate whether polyurethane foam leads more intense foreign-body reaction than silicone foam. To compare the vascularization of the capsules surrounding the foam implants. To investigate if the capsule of polyurethane foam implanted has greater amount of collagen than that of silicone foam. METHODS: Sixty-four young male Wistar rats were allocated into two groups: polyurethane foam and silicone foam. Subcutaneous discs were implanted into the dorsum of the animals in both groups. The capsules we… Show more

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Cited by 11 publications
(6 citation statements)
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References 19 publications
(12 reference statements)
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“…Giant cell reaction was observed in all samples, which is in agreement with other studies that compared textured implants to implants using different types of coverage 26,27,33,35 . Unlike Silva et al 28 , who found a moderate to intense presence of giant cell reaction in polyurethanecovered samples, it seems relevant to emphasize that in this study this variable was only classified as present or absent.…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…Giant cell reaction was observed in all samples, which is in agreement with other studies that compared textured implants to implants using different types of coverage 26,27,33,35 . Unlike Silva et al 28 , who found a moderate to intense presence of giant cell reaction in polyurethanecovered samples, it seems relevant to emphasize that in this study this variable was only classified as present or absent.…”
Section: Discussionsupporting
confidence: 92%
“…The rat (Rattus norvegicus albinus) chosen by the authors is the most used animal in capsular contracture studies, for presenting easy reproducibility of results and resistance to surgical procedures [25][26][27] .…”
Section: Discussionmentioning
confidence: 99%
“…One of the possible risks for the development of SSI with NPWT is that the polyurethane foam acts as a foreign body, generating an inflammatory reaction in the wound [41], as well as impacting on wound healing by failing to reduce the extent of bacterial colonization [42]. There have been recent reports of the bacterial burden not being altered by the use of NWPT [31].…”
Section: Discussionmentioning
confidence: 99%
“…Scales et al 2 defined the properties of an ideal implant: no physical change in tissue; chemically inert; non carcinogenic; non allergic or foreign body reactive; mechanical forces resilience; and made into the desired shape. Unfortunately, there is no such implant, but a lot of progress has been made, since its introduction in 1962 with Cronin and Gerow, to the current generation's implants 2 .…”
Section: Introductionmentioning
confidence: 99%