2009
DOI: 10.1590/s0102-86502009000300007
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: PURPOSE: To assess the proliferation and differentiation of human bone marrow-derived cells cultured on titanium surfaces with different roughness characteristics. METHODS: Cells obtained from the iliac crest of an adult human donor were routinely processed and cultured on titanium surfaces of varying roughness, according to their preparation method: polishing only (smooth surface) and polishing followed by etching with HF/HNO3 for 15 and 30 minutes (rough surfaces). Surfaces were assessed using scanning elect… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
18
0

Year Published

2012
2012
2022
2022

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 30 publications
(19 citation statements)
references
References 16 publications
(21 reference statements)
1
18
0
Order By: Relevance
“…It was shown by Zhou et al [38] that the percentage of fully spread epithelial-like cells among attached cells and cell density on 13 nm rough magnetron-sputtered TiO 2 coating was higher after 16 h of incubation compared to 5 nm rough coated samples. Furthermore, considering the crystalline structure of the obtained oxide, this anatase crystal architecture would be more beneficial for decreased bacterial proliferation because it has been found that amorphous TiO 2 promotes bacterial attachment [39]. Colon et al reported that, in contrast to the microstructured surface, nanostructured TiO 2 reduced Staphylococcus epidermidis adhesion and increased osteoblast functions, alkaline phosphatase activity, and calcium mineral deposition [40].…”
Section: Resultsmentioning
confidence: 99%
“…It was shown by Zhou et al [38] that the percentage of fully spread epithelial-like cells among attached cells and cell density on 13 nm rough magnetron-sputtered TiO 2 coating was higher after 16 h of incubation compared to 5 nm rough coated samples. Furthermore, considering the crystalline structure of the obtained oxide, this anatase crystal architecture would be more beneficial for decreased bacterial proliferation because it has been found that amorphous TiO 2 promotes bacterial attachment [39]. Colon et al reported that, in contrast to the microstructured surface, nanostructured TiO 2 reduced Staphylococcus epidermidis adhesion and increased osteoblast functions, alkaline phosphatase activity, and calcium mineral deposition [40].…”
Section: Resultsmentioning
confidence: 99%
“…Though Ti surface supported the cell proliferation, the data captured on the percentage of growth (cell count on 20 th day of culture period/seeding density×100) with all the three different seeding densities was an average of 3.2 times only while it was 21.3 times on control plastic surface. Here, from our data, we speculate that the Ti surface to be only cell friendly but not aiding in cell growth in comparison to the coated plastic surface though some authors [2] advocated that implant surface roughness, achieved by specific texturization techniques, favor cell responses. Additionally, we argue that cell differentiation is a key property of stem cell population that could be studied and evaluated in the cultured stem cell-Ti composite with regards to bone integration or ectodermal lineage differentiation studies though the cell proliferation is not an event that we documented.…”
Section: Letter To the Editormentioning
confidence: 66%
“…A stable, tissue friendly biological and not inert interface between the biomaterial surface and the surrounding tissue is a vital prerequisite both for immediate implant loading and for the long-term success of such implants. The interface is usually achieved by the biological process (partially regulated by mechanical and material properties) known as osseointegration of the implant, which is an intimate connection of the implant within the bone by means of an appropriate and sufficient growth of new bone on the surface of the implant [2]. Achieving a good osseointegration depends on physiological variables of the milieu along with particular properties of the implant material such as biocompatibility of the surface and the surface properties.…”
Section: Letter To the Editormentioning
confidence: 99%
“…Experimental results indicate that a rough surface is superior to a fine surface regarding cell adhesion and differentiation. Polishing and acid etching were also utilized to obtain different surface roughness on Ti samples [8]. In vitro experiments exhibit a low cell proliferation lever and a high differentiation degree on a coarse surface.…”
Section: Morphological Methodsmentioning
confidence: 99%