Conflito de interesses em pesquisa clínica

Abstract

In clinical research there is a real possibility to have some conflict of interests. Even for the researcher, the identification of these conflicts cannot be clear. There are many aspects to be considered, involving all participants of the process: the research subject, the researcher, the institution where the research is carried through, the sponsor, the ethics committees, the regulating agencies, the scientific community and the society. The conclusion is that conflicts of interests are common and inevitable in the academic field. The challenge is not to eradicate them, but to recognize them and to manage them properly. The only acceptable way to do this is to expose clearly the conflicts of interests and always to submit the clinical research projects to the ethics committees.

Integridade científica e pesquisa em saúde no Brasil: revisão da literatura

“…Conflicts of interest in clinical research emerged as a relevant topic that causes concern among researchers who propose the discussion on scientific integrity 14,17,27 . An issue related to the interface between financing coming from the pharmaceutical industry and the distribution of knowledge as a strategic component for the process of attention in public health also arose 17 .…”

“…The authors point out that conflicts of interest are inevitable and constitutive of academic life and scientific practice. The great challenge, then, is not their eradication but to approach them transparently, because their recognition allows for their proper management 14 .…”

Entendimento do termo de consentimento por pacientes partícipes em pesquisas com fármaco na cardiologia

“…Also in our study, 25% of individuals accepted the invitation to take part in the trial upon their doctor's request or recommendation. The words of a doctor may change the course of life or exercise great influence on a patient's 20 decision, not to mention the permanent possibility of conflicts of interest in trials sponsored by the pharmaceutical industry 21,22 .…”

Ética E Integridade: Condutas Para Produções Científicas No Brasil

“…• Conflito de interesses: é a incompatibilidade entre interesses pessoais e as obrigações de um indivíduo. Os autores exemplificam o conflito de interesses na medicina, quando o bem estar de um paciente pode ser prejudicado por interesses secundários como, por exemplo, ganho financeiro (11) .…”