2006
DOI: 10.1590/s0102-86502006000500012
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Abstract: Purpose: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. Methods: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bon… Show more

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Cited by 3 publications
(3 citation statements)
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“…Implantation of flakes of castor oil resin in rat dental alveolus showed a close contact with the newly formed bone in some regions, as the relative volume of bone trabeculae increased . On the other hand, some authors noted a capsule formed by fibrous connective tissue involving the polymer (18,19). In the present study, implanting the polymer in the subcutaneous layer of the skin, osteogenic tissue formation was not observed, questioning the osteoinduction activity of the material.…”
Section: Discussioncontrasting
confidence: 75%
“…Implantation of flakes of castor oil resin in rat dental alveolus showed a close contact with the newly formed bone in some regions, as the relative volume of bone trabeculae increased . On the other hand, some authors noted a capsule formed by fibrous connective tissue involving the polymer (18,19). In the present study, implanting the polymer in the subcutaneous layer of the skin, osteogenic tissue formation was not observed, questioning the osteoinduction activity of the material.…”
Section: Discussioncontrasting
confidence: 75%
“…The biocompatibility of the castor bean polymer, that is, the acceptance of the organism concerning the implanted material without significant inflammatory focus signals and no foreign body granulomatous reaction was observed in this study in all groups and has been highlighted by several authors after implant in bone defects 10,11 . In this research it was initially noticed the presence moderate to mild inflammatory infiltrate that decreased with time elapsed, but this difference was not statistically significant in Group B.…”
Section: ■ Discussionsupporting
confidence: 66%
“…[3] However, the regenerative capacity of bone tissue is limited by the extent of the injury, in this sense, extensive bone defects caused by trauma, tumors, infections, and developmental abnormalities do not regenerate spontaneously, posing a challenge to the scientific community. [4]…”
Section: Introductionmentioning
confidence: 99%