2006
DOI: 10.1590/s0102-86502006000400006
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Abstract: Subdiaphragmatic aortic cord cross-clamping is not a suitable rat model for spinal cord ischemia/reperfusion injury study as it does not ensure changes in in vivo tissue metabolites concentrations similar to those found in tissues subjected to ischemia/reperfusion.

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Cited by 4 publications
(2 citation statements)
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“…After the retroperitoneal area was opened, the abdominal aorta and inferior vena cava were identified and isolated. Spinal cord ischemia was created by clamping the aorta just below the renal vein with a medium-pressured aneurysm clip for 30 minutes as observed in previous studies (Yaşargil aneurysm clip, Aesculap) [15, 16].…”
Section: Methodsmentioning
confidence: 99%
“…After the retroperitoneal area was opened, the abdominal aorta and inferior vena cava were identified and isolated. Spinal cord ischemia was created by clamping the aorta just below the renal vein with a medium-pressured aneurysm clip for 30 minutes as observed in previous studies (Yaşargil aneurysm clip, Aesculap) [15, 16].…”
Section: Methodsmentioning
confidence: 99%
“…3,5,6 Although occlusion of the infrarenal aorta can avoid the ischemia of the abdominal organs, the scope of the spinal artery blocked in this way is small and cannot cause sufficient SCII. [7][8][9] Moreover, the mechanism of this method is different from that of clinical SCII, which leads to the deviation between animal experiments and clinical studies.…”
Section: Introductionmentioning
confidence: 99%