Análise tensional e morfológica da anastomose colônica na colite induzida por ácido acético a 10%, em ratos Wistar, tratados com extrato aquoso de aroeira-do-sertão a 10% (Myracrodruon urundeuva fr. all.)

RESUMO:Uma busca foi realizada na literatura, visando sumarizar as pesquisas realizadas e obter informações acerca da utilização de plantas medicinais no processo de cicatrização de feridas. Utilizaram-se os descritores: Plantas Medicinais e Cicatrização de Feridas e seus equivalentes em inglês e espanhol, com o operador booleano "AND" em três bases eletrônicas de dados (PubMed, LILACS e COCHRANE). Foram selecionados 57 artigos para compor a revisão. Os resultados apontam que um total de 52 plantas medicinais e um composto de ervas foram estudados experimentalmente ou clinicamente, quanto aos seus efeitos no auxílio do processo de cicatrização, sendo que a maioria (88,5%) apresentou eficácia. Com isso, verificase que a utilização de plantas medicinais trata de importante alternativa no tratamento de feridas, que começa a fazer parte da atenção à saúde brasileira, o que sugere novos estudos de comprovação clínica, custos, e benefícios e a constante atualização acerca das publicações realizadas.Palavras chave: extratos vegetais, fitoterapia, saúde pública, cicatrização.ABSTRACT: Medicinal plants in the wound healing process: a literature review. It was done a literature search aiming to sumarize earlier conducted researches and in order to obtain information on the use of medicinal plants in wound healing process. The descriptors used were as follows: Medicinal Plants and Wound Healing and their equivalents in English and Spanish with the Boolean operator "AND" in three electronic databases (PubMed, LILACS and COCHRANE). Fifty seven articles were chosen to compose the review. The findings from a total of fifty two medicinal plants and one herbal compound that were experimentally or clinically studied in respect to their effects in wound healing process indicate that the majority of them (eighty eight point five per cent) showed efficacy. Thus, it can be seen that the use of medicinal plants is an important alternative in wounds treatment that becomes part of Brazilian health care, suggesting further studies of clinical evidence, costs and benefits and constantly updating on produced publications.

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Plantas medicinais no processo de cicatrização de feridas: uma revisão de literatura

Piríz

Lima

Jardim

et al. 2014

Rev. bras. plantas med.

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Comparative studies between the chemical constituents and biological properties of the extracts from the leaves and barks of Myracrodruon urundeuva Fr. All.

Mota¹,

Royo²,

Fonseca³

et al. 2015

J. Med. Plants Res.

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The present study describes the comparation between the chemical constituents and biological properties of leaves and barks of Myracrodruon urundeuva for proposing the medicinal use of the plant from leaves, avoiding the degradation by remotion of the barks. The results of chromatographic profile of the hydroalcoholic extracts and fractions of leaves and barks showed similarities in the composition of the phytoconstituents, with variation for some of them that are in greater quantity of the bark extracts. The hydroalcoholics extracts from leaves (HELMu) and barks (HEBMu) exhibited promising 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (IC 50 = 4.8 and 7.0 µg/ml, respectively), comparable to gallic acid (IC 50 = 4.8 µg/ml). No significant cytotoxicity was observed in the concentrations evaluated (IC 50 > 400 μg/ml). The HEBMu exhibited greater nociceptive activity than HELMu, however HELMu was more active against oral pathogens. This study provides support for the use of the leaves in traditional medicine instead of bark.

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Antimicrobial activity and synergistic effects of an ethyl acetate fraction from methanol extract of Myracrodruon urundeuva bark

Jandú¹,

Silva²,

Silva³

et al. 2015

J. Med. Plants Res.

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Análise tensional e morfológica da anastomose colônica na colite induzida por ácido acético a 10%, em ratos Wistar, tratados com extrato aquoso de aroeira-do-sertão a 10% (Myracrodruon urundeuva fr. all.)

Abstract: The 10% aroeira-do-sertão aqueous extract, has healing activity on the colonic anstomosis during the occurrence of 10% acetic acid induced colitis. It improves the resistance to tension on the colonic anastomosis zone on the 3rd day.

Cited by 3 publications

References 9 publications

Plantas medicinais no processo de cicatrização de feridas: uma revisão de literatura

Plantas medicinais no processo de cicatrização de feridas: uma revisão de literatura

Comparative studies between the chemical constituents and biological properties of the extracts from the leaves and barks of Myracrodruon urundeuva Fr. All.

Antimicrobial activity and synergistic effects of an ethyl acetate fraction from methanol extract of Myracrodruon urundeuva bark

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