Effect of splenectomy and ligature of the left gastric vein on portal hypertensive colopathy in carriers of surgical hepatosplenic schistosomiasis mansoni

Justo, C. R. E.; Brandt, Carlos Teixeira; Lucena, Maurilio Toscano de; Jales, Martha

doi:10.1590/s0102-86502005000100003

Cited by 5 publications

(2 citation statements)

References 12 publications

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“…The splenic artery ligation in early splenectomy allows the output of blood by the spleen splenic vein and reduces the size of the spleen due to the inflow of splenic blood into the portal circulation [22][23][24][25] . According to the literature during the removal of larger spleens there is inflow of more than 500 ml of whole blood 1 .…”

Section: Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Haematological and biochemical characteristics of the splenic effluent blood in schistosomal patients undergoing splenectomy

Petroianu

Buzatti

Resende

et al. 2014

Rev. Col. Bras. Cir.

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Section: Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Haematological and biochemical characteristics of the splenic effluent blood in schistosomal patients undergoing splenectomy

Petroianu

Buzatti

Resende

et al. 2014

Rev. Col. Bras. Cir.

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“…The effect of such surgery on PHC is unclear. In one study, adolescents with hepatosplenic schistosomiasis and PHC showed vascular alterations at colonoscopy after they had undergone surgical treatment for decompression of the portal vein (10) . There are no follow up data on the behavior of PHC after portal decompressive surgery in adult patients.…”

Section: Introductionmentioning

confidence: 99%

Improvement of Schistosomal Portal Hypertensive Colopathy After Surgical Treatment

Miranda

Ferraz

Domingues³

et al. 2013

Arq. Gastroenterol.

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-Context -Data on vascular alterations in patients with hepatosplenic schistosomiasis and portal hypertensive colopathy and changes in these after surgery to decrease portal hypertension are limited. Objective -The purpose of this study was to analyse the alterations of portal hypertensive colopathy previously and 6-12 months after splenectomy and gastric devascularization. Methods -Twelve patients with hepatosplenic schistosomiasis who also had upper gastrointestinal bleeding were studied prospectively. Their endoscopic findings before and 6-12 months after the surgery were analysed. In addition, mucosal biopsies from ascending colon, sigmoid colon and rectum at these time points were subjected to histological and histomorphometric assessment. It was used a control group due to lack of normal pattern of the histomorphometric measures of vessels in individuals without portal hypertension. The critical level of significance adopted in all tests was of a maximum probability error of 5%. Results -Surgery did not lead to significant improvement in histological and endoscopic findings. However, on histomorphometry, there was a significant decrease in the area, diameter and thickness of the vessels in mucosa at all colonic sites. Conclusion -Surgery for decompression of schistosomal portal hypertension has a beneficial effect on the associated colopathy, being best indicated in patients with gastrointestinal bleeding and esophageal varices. HEADINGS -Hypertension, portal. Schistosomiasis mansoni. Colonic diseases. Microvascular descompression surgery.

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Alterations in colonic mucosal lesions in patients with portal hypertension

Kady

Hamdy

Mostafa³

et al. 2009

Arab Journal of Gastroenterology

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Effect of splenectomy and ligature of the left gastric vein on portal hypertensive colopathy in carriers of surgical hepatosplenic schistosomiasis mansoni

Abstract: Splenectomy and ligature of the left gastric vein tend to reduce the abnormal vascular findings of PHC in carriers of hepatosplenic schistosomiasis mansoni.

Cited by 5 publications

References 12 publications

Haematological and biochemical characteristics of the splenic effluent blood in schistosomal patients undergoing splenectomy

Haematological and biochemical characteristics of the splenic effluent blood in schistosomal patients undergoing splenectomy

Improvement of Schistosomal Portal Hypertensive Colopathy After Surgical Treatment

Alterations in colonic mucosal lesions in patients with portal hypertension

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