2004
DOI: 10.1590/s0102-86502004000500018
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: PURPOSE:To determine the effects of 30 minutes of ischemia followed by 30 minutes of reperfusion in skeletal muscle of rats receiving three different diets (supplemented, normal and vitamin E deficient) on lipoperoxidation (LP). METHODS: LP measured by TBARS levels, and plasma and hepatic concentrations of vitamin E measured by HPLC. RESULTS:The deficient group presented higher lipoperoxidation levels in muscle compared to the control and supplemented groups. CONCLUSION: Supplementation with vitamin E decrease… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
1
0
4

Year Published

2007
2007
2014
2014

Publication Types

Select...
2
1

Relationship

1
2

Authors

Journals

citations
Cited by 3 publications
(5 citation statements)
references
References 8 publications
0
1
0
4
Order By: Relevance
“…Some studies have shown that vitamin E has a protective effect, averting I/R injuries to skeletal muscle. 9 Drugs that act on the endothelium and on vascular reactivity have also been studied. For example, cilostazol and pentoxifylline (employed to manage chronic ischemia) and pravastatin and simvastatin (used to reduce cholesterol) have been shown to attenuate I/R injuries to skeletal muscle.…”
mentioning
confidence: 99%
“…Some studies have shown that vitamin E has a protective effect, averting I/R injuries to skeletal muscle. 9 Drugs that act on the endothelium and on vascular reactivity have also been studied. For example, cilostazol and pentoxifylline (employed to manage chronic ischemia) and pravastatin and simvastatin (used to reduce cholesterol) have been shown to attenuate I/R injuries to skeletal muscle.…”
mentioning
confidence: 99%
“…Como pode ser visto na Figura 1 na próxima página, após a revascularização, a entrada de O 2 em áreas isquêmicas, predispõe a formação de espécies reativas de oxigênio (ERO) (MCCORD 1983;AKIMITSU, GUTE, JEROME 1994), moléculas instáveis e altamente reativas, extremamente tóxicas para o metabolismo celular (AKIMITSU, GUTE, JEROME 1994;SILVEIRA, YOSHIDA 2004 (GUTE et al, 1998); e ainda, aumentar a permeabilidade microvascular (RUBIN et al, 1996;GUTE et al, 1998;SOUZA et al, 2001). 1987;FORMAN, VIRMANI, PUETT 1990;TURRENS et al, 1991;MARCEAU, HESS, BACHVAROV 1998;PAN et al, 2000;SOUZA et al, 2001;PICCINATO et al, 2004b;YANG et al, 2004;GROSS, GROSS 2006;KLONER, REZKALLA 2006;ZHAO, VINTEN-JOHANSEN 2006;ELIASON, WAKEFIELD 2009;MEDLING et al, 2009;WANG et al, 2009;WANG et al, 2010 (KOKSAL et al, 2003;KEARNS et al, 2004;ALVES et al, 2010;WANG et al, 2010).…”
Section: Fisiopatologiaunclassified
“…As lesões musculares devido a SIR podem ser determinadas de diferentes maneiras desde a dosagem de marcadores bioquímicos como a AST, a CPK e a LDH (ANAYA-PRADO et al, 2002) até a determinação da taxa de controle respiratório (RCR) e do potencial de membrana mitocondrial para quantificação da fosforilação oxidativa (BRANDÃO et al, 2003). A ação das ERO sobre os fosfolípides da membrana celular promove liberação de produtos de degradação desta membrana como o MDA e este pode ser usado como marcador de lesão (GRISOTTO et al, 2000;FREITAS et al, 2002;KOKSAL et al, 2003;PICCINATO et al, 2004b;ALVES et al, 2010).…”
Section: Marcadores De Isquemia E Reperfusãounclassified
See 2 more Smart Citations