2004
DOI: 10.1590/s0102-86502004000500011
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Conseqüências no crescimento de maxila e mandíbula de defeito ósseo cirúrgico no ramo da mandíbula de ratos

Abstract: OBJETIVO: Analisar as conseqüências no crescimento de maxila e mandíbula de defeito ósseo cirúrgico simulando fratura no ramo da mandíbula. MÉTODOS: Foram utilizados 25 ratos Wistar com um mês de idade. Sob anestesia geral e por meio de incisão submandibular. Foi realizada osteotomia vertical no ramo da mandíbula do lado direito com emprego de motor cirúrgico. Após período de dois meses os animais foram sacrificados, os tecidos moles retirados e as hemimandíbulas desarticuladas. Foram realizadas incidências ra… Show more

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Cited by 5 publications
(6 citation statements)
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“…Cephalometric evaluations from radiographs of dissected specimens using a computer system lead to reliable measurements, reducing technical difficulties 16 . Distances found were similar to those noted in other experiments [17][18][19][20] . Only structures which do not underwent direct influence of the fracture were used as reference points 16,18,19 .…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…Cephalometric evaluations from radiographs of dissected specimens using a computer system lead to reliable measurements, reducing technical difficulties 16 . Distances found were similar to those noted in other experiments [17][18][19][20] . Only structures which do not underwent direct influence of the fracture were used as reference points 16,18,19 .…”
Section: Discussionsupporting
confidence: 90%
“…Distances found were similar to those noted in other experiments [17][18][19][20] . Only structures which do not underwent direct influence of the fracture were used as reference points 16,18,19 . In this study deviation of the median line of the mandible in relation to the maxillary median line was observed in the fracture and undernourished fracture groups.…”
Section: Discussionsupporting
confidence: 90%
“…4 Also, osteotomies that simulated a mandibular fracture in the growing period had as consequences asymmetries of the maxilla and the mandible, 5 or lessening of the mandible. 6 It has been demonstrated that the masticatory muscle function is a determinant of the quality of bone of the growing mandible. 7 The elevator muscles infl uence the transversal and the vertical dimensions of the face.…”
Section: Introductionmentioning
confidence: 99%
“…O processo de reparo ósseo pode ser estudado por diversos modelos experimentais (AGUIAR, 2008;BOMBONATO;BRENTEGANI, 1997;FLACH et al, 2008;GRANSTROM;NILSSON, 1987). Porém, este modelo tem sido empregado com bastante sucesso em nosso departamento, em pesquisas que avaliaram o processo de reparo ou de crescimento ósseo (AGUIAR, 2008;RABEQUE et al, 2002;RODRIGUES;MIYAZAKI;LUZ, 2004). O rato é um animal de pequeno porte, de fácil manuseio e custo acessível, podendo ser usado em quantidades numerosas, e as lesões ósseas confeccionadas por meio de brocas proporcionam formas homogêneas.…”
Section: Período De Observaçãounclassified
“…LAMANO CARVALHO, 2001). Por outro lado o modelo de defeito ósseo mandibular simulando fratura permite a avaliação do processo de reparo por meio da formação de calo ósseo, sem comprometer significativamente a mastigação do animal (AGUIAR, 2008;RABEQUE et al, 2002;RODRIGUES;MIYAZAKI;LUZ, 2004). Até o presente momento nenhum estudo prévio foi feito para avaliar os efeitos da amlodipina no processo de reparo de fatura mandibular ou de qualquer outra fratura óssea.…”
Section: Introductionunclassified