Submucosa de intestino delgado no reparo de defeito em parede abdominal de ratos

Greca, Fernando Hintz; Filho, Zacarias Alves de Souza; Rocha, Sérgio Luiz; Borsato, Karin Soldatelli; Fernandes, Heitor Augusto Dalarossa; Niiside, Marco Aurelio

doi:10.1590/s0102-86502004000500004

Cited by 6 publications

(14 citation statements)

References 11 publications

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“…Isa [43] and Aramayo, et al [37] used different kinds of surgical meshes and recorded adhesions as well as Greca, et al [15] and Canellas [36] that reported, respectively, intestinal adhesion in 4% and omentum adhesion in 5% of rats underwent polypropylene mesh implant in abdominal wall.…”

Section: Discussionmentioning

confidence: 99%

“…A wide variety of biomaterials such as bovine pericardium [10] [11], bovine peritoneum [12], bubaline aortic matrix [13], bubaline diaphragm [14], porcine small intestinal submucosa [15], caprine rumen [14], ovine tunica albuginea [16] [17] and dog tunica albuginea [18] have been reported as biologic scaffolds in abdominal wall repair surgery. In this regard, various studies have shown tunica albuginea as a useful biologic mesh due to its low cost, easy collection, conservation, processing and application technique [16]- [22].…”

Section: Introductionmentioning

confidence: 99%

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Heterologous Bovine Tunica Albuginea Graft Conserved in Honey as Abdominal Wall Reinforcement in Rats

Medeiros¹,

Ferreira²,

Castañon³

et al. 2020

OJVM

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Complex abdominal wall defects might be challenging for human and veterinary surgeons worldwide. Defects from trauma or congenital causes may lead to hernias development. The introduction of meshes to reinforce hernia repairs has improved surgical outcomes and several synthetic and biologic materials have been used. In this context, biomaterial prosthesis seems to be a satisfactory solution when managing great abdominal wall defects. The aim of the current study is to evaluate the bovine tunica albuginea (BTA) preserved in honey as graft material for rats' abdominal wall reinforcement in incisional herniorrhaphy surgery as well as its viability, cicatrization and integration into the host tissue. Wistar rats were assigned to two main groups: 1) animals (n = 20) underwent median longitudinal laparotomy followed by laparorraphy with suture of the bovine tunica albuginea (BTA) graft as abdominal wall reinforcement; and 2) animals (n = 20) underwent only laparotomy and subsequent laparorrhaphy. Rats were clinically evaluated until euthanasia at post-surgical day 7, 14, 21 and 28. Necropsy and histopathological analysis of abdominal wall fragments were performed to compare groups and subgroups findings. BTA promoted abundant fibrosis, providing resistance and low postoperative complication rates. Besides, animals did not show rejection signs to the implant. In conclusion, BTA preserved in honey is an affordable, easy collection and handling biomaterial for graft, demanding simple surgical implantation technique for abdominal wall repair in rats.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Heterologous Bovine Tunica Albuginea Graft Conserved in Honey as Abdominal Wall Reinforcement in Rats

Medeiros¹,

Ferreira²,

Castañon³

et al. 2020

OJVM

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“…O sulfato de neomicina a 10% mostrou-se satisfatório em relação à eliminação de bactérias pertinentes à área de enxertia, assim como já descrevia GRECA et al (2004a;2004b;2005) e SOUZA FILHO et al (2004;2005).…”

Section: Nota-se Reepitelização Completa (Setas Menores) E a Regeneraunclassified

Uso Da Submucosa Intestinal Porcina Conservada Em Sulfato De Neomicina Na Enxertia Esofágica Em Cão

Villanova¹,

Daleck²,

Wouk³

et al. 2006

AVS

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RESUMO -Verificou-se a eficácia da submucosa intestinal porcina como alternativa para substituir três centímetros de esôfago cervical em cão, e o uso de sulfato de neomicina como meio de conservação desta membrana biológica. Nestes estudos foram utilizados dezesseis cães adultos, sendo quatro avaliados durante sete dias, quatro durante 15 dias, quatro durante 30 dias e os restantes avaliados durante 45 dias de período pós-operatório. A avaliação pós-operatória constitui-se de exames clínicos e laboratoriais, e ao final do período de acompanhamento, foram submetidos à eutanásia para exame de necropsia e colheita da área enxertada para avaliação histopatológica. Este trabalho possibilitou concluir que o emprego desta membrana biológica na forma como foi conservada, permite a substituição de parte de esôfago cervical canino, proporcionando rápida e completa proliferação epitelial. A área de enxertia aos 30 dias do período pós-operatório mostrou-se ineficaz sob o ponto de vista funcional, nas medidas estudadas (substituição de três centímetros de esôfago cervical), pois ocorreram em todos os animais operados, estenoses e conseqüentemente engasgos, hiporexia, desnutrição e caquexia. Os autores consideram que o esôfago continua sendo um desafio cirúrgico.Palavras-chave: anastomose esofágica; membrana biológica; enxerto; sulfato de neomicina; cirurgia.ABSTRACT -It has been verified the effectiveness of the porcine intestinal submucous as an alternative to replace three centimeters of cervical esophagus in dog and the use of neomycin sulphate as a way for the conservation of this biological membrane. In these studies sixteen adult animals were used, four animals being evaluated for seven days, four for fifteen days, four for thirty days and the remaining four were observed for forty-five days after the surgery. The postoperative evaluation consists of clinical and laboratory examinations, and at the end of the post-operation followup period they were euthanized and underwent necropsy, the grafted area was harvested for a histopathological exam. This research made it possible to conclude that the use of a biological membrane, replacing part of the canine cervical esophagus is an executable method as it allows a quick epithelial proliferation. The area of graft at the 30 days after the surgery period showed, to be not functionally effective in the studied proportions (substitution of three centimeters of cervical esophagus) displaying in all the operated animals, stenosis and consequently chokes, hypoxia, lack of nutrition and cachexia. The authors consider that the esophagus follows being a surgical challenge.Key-words: esophagus anastomosis; biological membrane; graft; neomycin sulphate; surgery. IntroduçãoIntervenções operatórias esofágicas requerem, provavelmente, mais habilidade e precisão do que qualquer outra porção do trato alimentar, pois o esôfago é mais propenso à deiscência pós-operatória. Os principais elementos implicados no aumento do risco relativo de extravasamento ou deiscência no esôfago são: ausência d...

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“…More recently, biological materials have been used for the same purpose. Among these, swine small bowel submucosa [ 7 , 8 ], swine urinary bladder submucosa [ 9 ], bovine peritoneum [ 10 ], microbial cellulose membrane [ 11 ], and bovine pericardium [ 4 , 12 ] stand out. Collagen-based animal tissue has been more frequently used, associated to several conservation techniques to preserve its viability and reduce antigenicity [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Surgical treatment of traumatic eventration with polyester button and polypropylene mesh to strengthen the suture technique in equine

et al. 2016

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BackgroundDefects in the abdominal wall of horses have high relapse rate. This is mainly in lateral eventrations and hernias caused by trauma from kicks of other horses or installation structures. The eventration region normally becomes swollen and there may be complications due to intestinal loop incarceration. The surgical treatment, consisting of reconstruction of the abdominal wall, frequently require biological or synthetic materials for the reinforcement of the suture line and tension support. Therefore, several studies have reported new materials for the repair of the abdominal wall, with the aim of improving the integration among adjacent tissues and reducing risks and complications such as rejection and infection. This report describes for the first time the use of a regular polypropylene mesh reinforced with polyester buttons for the herniorrhaphy.Case presentationA male, three-year-old, Appaloosa with 500 Kg presented to our hospital with a 10 days history of an increased volume on the left ventro-lateral region of the abdomen. During the physical examination, a deventration following traumatic rupture of the abdominal wall was diagnosed via ultrasonography. Then, the equine was anesthetized and moved to surgery for correction of the eventration which was performed according to conventional technique described in literature. Two days later, an eventration relapse was observed and confirmed via ultrasonography. After that, a second surgical intervention was performed using polyester buttons and polypropylene mesh. After the second surgical procedure, no complications related to eventration were observed either intra or postoperatively. After that, a recheck was performed thirty days later where satisfactory wound healing and total recovery were observed.ConclusionThe use of polypropylene mesh reinforced with polyester buttons is an effective technique for the repair of traumatic eventration in horses. This technique provides effective reinforcement against the abdominal tension and was a good option for reconstruction of lacerated muscles in cases of equine post-traumatic eventration, including relapsing cases.

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Submucosa de intestino delgado no reparo de defeito em parede abdominal de ratos

Cited by 6 publications

References 11 publications

Heterologous Bovine Tunica Albuginea Graft Conserved in Honey as Abdominal Wall Reinforcement in Rats

Heterologous Bovine Tunica Albuginea Graft Conserved in Honey as Abdominal Wall Reinforcement in Rats

Uso Da Submucosa Intestinal Porcina Conservada Em Sulfato De Neomicina Na Enxertia Esofágica Em Cão

Surgical treatment of traumatic eventration with polyester button and polypropylene mesh to strengthen the suture technique in equine

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