2003
DOI: 10.1590/s0102-86502003000100009
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Abstract: OBJETIVO: Objetivou-se investigar os efeitos temporais da ligadura do ducto biliar principal, em ratos Wistar. MÉTODOS: Utilizaram-se 48 ratos machos distribuídos em 2 grupos e redistribuídos em 4 subgrupos (n=06), identificados pelo tempo estipulado para a coleta das amostras (12, 24, 48 e 168 horas). Após laparotomia, os animais foram submetidos à dissecção e passagem de dois fios circundando o ducto biliar principal, sem ligadura (Grupo 1) e com ligadura (Grupo 2. RESULTADOS: As concentrações das bilirrubin… Show more

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Cited by 2 publications
(3 citation statements)
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“…But, seven days after the procedure for biliary obstruction, the animals showed strongly yellow urine, skin and mucous membranes icteric, ranging from mild to severe; stools lighter shade than that observed before ligation, so as to hepatomegaly palpation. Signs compatibles with what is described on cholestasis in humans 1,48,49 , dogs 9,18 , mices 20 and rats 22,23 . However, in less time than that observed in other animal species researchs 20,22 .…”
Section: Discussionsupporting
confidence: 78%
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“…But, seven days after the procedure for biliary obstruction, the animals showed strongly yellow urine, skin and mucous membranes icteric, ranging from mild to severe; stools lighter shade than that observed before ligation, so as to hepatomegaly palpation. Signs compatibles with what is described on cholestasis in humans 1,48,49 , dogs 9,18 , mices 20 and rats 22,23 . However, in less time than that observed in other animal species researchs 20,22 .…”
Section: Discussionsupporting
confidence: 78%
“…However, Branco Filho et al 58 , reported that of 45 human nephrectomies performed using ligation of the renal vessels with two titanium clips and cotton thread, there was need for further surgery in six hours for ligating the renal artery in one case, whose titanium clips were released. Maia et al 23 , using only thread in the common bile duct ligation, in rats, results could obstructive, without describing complications during the experiment. Same situation described by Crema et al 18 in biliary obstruction experiment with dogs, and Dutra et al 59 , also rats.…”
Section: Discussionmentioning
confidence: 99%
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