2000
DOI: 10.1590/s0102-86502000000200005
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Abstract: A utilização de plantas medicinais é uma prática comumente observada nos países em desenvolvimento. Desta forma objetivou-se verificar os efeitos microscópicos do óleo de copaíba no fígado de ratos. Para tal foram utilizados 50 Rattus norvegicus albinus, machos, distribuídos em cinco grupos: Grupo Copaíba 0,63 (GC0,63 ml/Kg de óleo de copaíba), Grupo copaíba 0,06 (GC0,06 ml/Kg de óleo de copaíba), Grupo Água (GA0,63 ml/kg de água), Grupo milho (GM0,63 ml/Kg de óleo de milho) e grupo Padrão (GP). As substâncias… Show more

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Cited by 4 publications
(5 citation statements)
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“…These concentrations were much higher than those reported in this study, but these authors suggested its use for control of this mosquito. Based on the lethal concentrations, C. reticulata presented the most promising form, and its potential for use increased when referring to its non toxic activity for hepatic cells demonstrated by Brito et al (2000) in rats. 80 (79,01-83,99) 180 (170,01) Table 1.…”
Section: Abstract: Botanical Insecticide Elephantiasis Control Cumentioning
confidence: 99%
“…These concentrations were much higher than those reported in this study, but these authors suggested its use for control of this mosquito. Based on the lethal concentrations, C. reticulata presented the most promising form, and its potential for use increased when referring to its non toxic activity for hepatic cells demonstrated by Brito et al (2000) in rats. 80 (79,01-83,99) 180 (170,01) Table 1.…”
Section: Abstract: Botanical Insecticide Elephantiasis Control Cumentioning
confidence: 99%
“…The use of standard dosage copaiba (0.63 mL/Kg) does not significantly alter liver function, displaying only a fraction increases from direct bilirubin, but without showing signs of cholestasis 19,20 . However the use of higher doses (6 mL/Kg), changes the amount of AST, alkaline phosphatase and GT,…”
Section: Discussionmentioning
confidence: 94%
“…Copaiba oil stands out among the Amazonia`s medicinal plants due to be attributed to this an important anti-inflamatory effect 17,18 and a function that promotes protection in the liver tissue 19 .…”
Section: Introductionmentioning
confidence: 99%
“…That dose was based on popular indication for therapeutic usage, suggesting daily usage of 1 tablespoon a day (around 10mL) which, being applied the correction factor to a rodent metabolism (f=3) 14 , correspond to a volume of 0.42 ml/kg.…”
Section: Methodsmentioning
confidence: 99%