An evaluation of new circle system of anesthesia. Quantitative anesthesia with isoflurane in new zealand rabbits

Abstract

A small circuit system of anesthesia was developed by Fonseca and Goldenberg in 1993. The authors used in this study New Zealand White (NZW) rabbits under closed system anesthetic regiment by insoflurane. Twenty male adult New Zealand rabbits were distributed in two groups of ten animals. No premedicant drugs were given. Endotraqueal intubation was made after intravenous administration of propofol (10mg/kg). Insoflurane was used to anesthesia management, administred by lowflow closed system technique with cooper kettle vaporizer, fixed by pre-calculated vaporizing flow in double times intervals. The group II underwent surgical periostal scratching in the medial tibial surface at the proximal shaft. Rabbits breathed spontaneously. Hypotensio, hypercapnia and respiratory acidosis were characteristic of the cardiopulmonary effects of the anesthesia. The corneal reflex and pinch reflex was useful as reliable indicators of anesthesic depth. Manual or mechanical ventilation should be considered as a way of improving alveolar ventilation and normalize blood-gas values. The system developed by Fonseca and Goldenberg was considered suitable for anesthesic management in rabbits.

Cardiorespiratory variables, bispectral index and recovery of anesthesia in dogs anesthetized with isoflurane, treated or not with tramadol

“…As porcentagens de redução na PAM foram de 24,7% para os do GC e 35,8% para os do GT. Estes resultados confirmam os de outros autores, que são unânimes em afirmar que o isofluorano promove redução das pressões arteriais, e que esta é, ainda, dose dependente (Fonseca et al, 1997). Assim, as diminuições do PAS, PAD e PAM provavelmente estão relacionadas à redução da resistência vascular periférica (Omoigui, 1998), induzida pelo agente inalatório empregado.…”

“…2). O período de recuperação obtido nos animais do GC foi próximo ao registrado por Fonseca et al (1997), ou seja, de aproximadamente cinco minutos para TE e sete minutos para PE. Com relação ao GT, observaram-se médias do tempo de recuperação de aproximadamente três e seis minutos para TE e PE, respectivamente.…”