Abstract:Nuclear magnetic resonance spectroscopy (NMRS) is a powerful technique that enables continuous monitoring of biochemical processes in tissues and organs in a non-invasive manner. A model of isolated perfused rat pancreas, suitable for NMRS studies, was developed. Acute pancreatitis was induced by injections of either 0.5 ml 5% sodium taurocholate (TC) into the bile duets, or 1.0 ml 10% TC injections into the pancreatic parenchyma. Phosphorous (31P) NMRS of experimental pancreatitis were characterized by a tran… Show more
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