Recuperação pôndero-estatural em crianças com síndrome de Down e cardiopatia congênita

Bravo-Valenzuela, Nathalie Jeanne; Passarelli, Maria Lúcia Bastos; Coates, Maria Veronica; Nascimento, Luiz Fernando Costa

doi:10.1590/s0102-76382011000100013

Cited by 12 publications

(8 citation statements)

References 16 publications

(13 reference statements)

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“…Os avanços tecnológicos têm propiciado correções cirúrgicas que aumentam a sobrevida das crianças com cardiopatia e melhora da expectativa de vida deste grupo populacional, mas a prevalência de alterações cardíacas nessa população paira em torno de 40% a 50% 4 . No atual estudo, esse percentual encontrou-se dentro da estimativa preconizada na literatura.…”

Section: Discussionunclassified

“…O principal fator de risco para a ocorrência da síndrome é a idade materna avançada, notando-se aumento significativo a partir dos 35 anos, e com incidência de 1 para cada 30 nascidos vivos de mães com mais de 45 anos 2 . Alguns estudos mostram que a idade paterna avançada também pode ser um fator contribuinte 4 . Não existe evidência da ação de fatores hormonais, deficiências de vitaminas, drogas, toxinas, vírus ou fatores racial, social e econômico sobre a incidência da síndrome, nem dados de predileção por sexo 2 .…”

Section: Introductionunclassified

“…As manifestações fenotípicas mais comuns são a deficiência intelectual, hipotonia muscular, baixa estatura, anomalias faciais, mãos curtas, frequentemente com prega palmar única e malformações congênitas, especialmente as cardíacas 4 .…”

Section: Introductionunclassified

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A Influência Das Malformações Cardíacas Congênitas De Crianças Com Síndrome Do Cromossomo 21

Gonzaga

André²,

Oliveira³

et al. 2016

COLLOQ VITAE

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As malformações cardíacas afetam entre 40 e 50% dos casos com Síndrome de Down (SD) enquanto sua prevalência no recém-nascido sem SD varia de 40 a 60%. Existe uma incidência de cardiopatias congênitas (CC) significativamente superior nas mulheres com SD. Sendo assim, o objetivo do presente estudo foi comparar o desenvolvimento motor de bebês com SD de zero a quatro meses de idade que apresentavam ou não CC. Participaram 26 crianças com SD, com idade média de 3,84 ± 3,28 meses, frequentadoras de um centro de atendimento de fisioterapia e reabilitação da UNESP. Foi utilizado como instrumento o Inventário Portage Operacionalizado (IPO) e a anamnese realizada com os pais e posteriormente uma análise descritiva dos dados utilizando média, desvio padrão e porcentagem. Concluiu-se que o fator de risco cardiopatia não foi determinante para o atraso no desenvolvimento neuropsicomotor. Palavras-chave: Síndrome de Down, cardiopatias congênitas, desenvolvimento infantil, habilidades motoras, desvios do desenvolvimento infantil.

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Section: Discussionunclassified

Section: Introductionunclassified

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A Influência Das Malformações Cardíacas Congênitas De Crianças Com Síndrome Do Cromossomo 21

Gonzaga

André²,

Oliveira³

et al. 2016

COLLOQ VITAE

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“…Factors restricting growth potential are also implicated in growth retardation of cardiac patients, such as low birth weight, small for gestational age and associated genetic syndromes [ 7 , 11 , 17 ] .…”

Section: Discussionmentioning

confidence: 99%

“…The advancement of corrective surgeries had great impact on the improvement of growth and weight gain in these patients [ 11 - 14 ] , but it always dependent on factors such as the severity of the initial underdevelopment, the presence or absence of cyanosis, the hemodynamic status, pre-natal causes and fundamentally the type of disease [ 12 - 20 ] .…”

Section: Introductionmentioning

confidence: 99%

Evolution of weight and height of children with congenital heart disease undergoing surgical treatment

Peres¹,

Croti²,

Godoy³

et al. 2014

Revista Brasileira De Cirurgia Cardiovascular

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ObjectiveTo evaluate the height and weight development of children with congenital heart disease undergoing surgery with the goal of determining when they reach the threshold of normal development and whether there are differences between patients with developmental pattern below the level of normality preoperatively (z-score<-2 for the analyzed parameter) in comparison to the total group of cardiac patients.MethodsWe prospectively followed up 27 children undergoing operation into five time periods: preoperatively and at four subsequent outpatient appointments: 1st month, 3rd month, 6th month and 12th month after hospital discharge. The anthropometric parameters used were median z-score (MZ), weight (WAZ), height (HAZ), subscapular skinfold (SSFAZ), upper arm circumference (UAC) and triceps skinfold (TSFAZ). The evolution assessment of the parameters was performed by analysis of variance and comparison with the general normal population from unpaired t test, both in the total group of cardiac patients, and in subgroups with preoperative parameters below the normal level (Zm<-2).ResultsIn the total group there was no significant evolution of MZ of all parameters. WAZ was statistically lower than the normal population until the 1st month of follow-up (P=0.028); HAZ only preoperatively (P=0.044), SSFAZ in the first month (P=0.015) and at 12th month (P=0.038), UAC and TSFAZ were always statistically equal to the general population. In patients whose development was below the level of normality, there were important variation of WAZ (P=0.002), HAZ (P=0.001) and UAC (P=0.031) after the operation, and the WAZ was lower than the normal population until the 3rd month (P=0.015); HAZ and UAC, until the first month (P=0.024 and P=0.039 respectively), SSFAZ, up to the 12th month (P=0.005), the TSFAZ only preoperatively (P=0.011).ConclusionThe operation promoted the return to normalcy for those with heart disease in general within up to three months, but for the group of patients below normal developmental pattern of the return occurred within 12 months.

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Gain in growth after surgical repair of congenital heart disease among children with Down syndrome

Saquib

Sarraj

Oubaied

et al. 2021

American J of Med Genetics Pt A

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Down syndrome (DS) is a common genetic disorder among Saudi children, for which limited data is available on growth for those who undergo surgery for congenital heart disease (CHD). We assessed the magnitude of growth over time following surgery and the factors associated with growth change. Eighty-eight children with DS and CHD who underwent surgery between 2009 and 2017 at the tertiary children's hospital in Al-Qassim, Saudi Arabia, were eligible. Information on gender, height, and weight (at surgery, 6 and 12 months), age at surgery, and type of CHD were abstracted from the medical records. Repeated measure analysis of variance (ANOVA) was used for data analysis. The sample's mean age (SD) was 16.2 months (20.1); 47% were male. Height, weight, and body mass index (BMI) increased significantly at both follow-up points. There was a significant interaction between age at surgery, type of heart disease, and time for all three physical indices (p-values <0.001). The increase in height, weight, and BMI was significantly greater for children ≤8 months old with acyanotic CHD compared to children >8 months with cyanotic CHD. Overall, the gain in growth was greater for the children with DS who had had surgery at a younger age.

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Recuperação pôndero-estatural em crianças com síndrome de Down e cardiopatia congênita

Cited by 12 publications

References 16 publications

A Influência Das Malformações Cardíacas Congênitas De Crianças Com Síndrome Do Cromossomo 21

A Influência Das Malformações Cardíacas Congênitas De Crianças Com Síndrome Do Cromossomo 21

Evolution of weight and height of children with congenital heart disease undergoing surgical treatment

Gain in growth after surgical repair of congenital heart disease among children with Down syndrome

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