Efeitos da radiação gama no comportamento mecânico e na calcificação do pericárdio bovino fixado com glutaraldeído

Abstract

Efeitos da radiação gama no comportamento mecânico e na calcificação do pericárdio bovino fixado com glutaraldeídoEffects of gamma irradiation on mechanical behavior and calcification of glutaraldehyde-fixed bovine pericardium Abstract Objective: To evaluate the effect of gamma irradiation on glutaraldehyde-fixed bovine pericardium.Method: Glutaraldehyde-fixed bovine pericardium was exposed to gamma radiation (doses from 0 to 10000 Gy). Six samples from each of nine groups were evaluated by optic microscopy, and shrinking and mechanical tests and the denaturation temperature was determined. Additionally, they were subcutaneously implanted in rats and after four months they were explanted and Ca 2+ levels measured by atomic absorption spectroscopy.Results: The Ca 2+ levels were (in µg/mg): control