volume 22, issue 1, P131-136 2012
DOI: 10.1590/s0102-695x2011005000178
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Abstract: Abstract: Several species of Solanum are used in folk medicine to treat diarrhea. Therefore, the aim of this study was to investigate and compare possible antidiarrheal activity of methanol extracts from roots (Sast-MeOH R ) and leaves (Sast-MeOH L ) of Solanum asterophorum Mart., Solanaceae, in mice. Sast-MeOH R was shown to significantly and dose-relatedly inhibit the frequency of both solid (ED50 309.6±28.5 mg/kg) and liquid (ED50 152.1±32.5 mg/kg) stools. Conversely, SastMeOH L significantly inhibited sol…

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