Therapeutic value of the genus Alpinia, Zingiberaceae

Victório, Cristiane Pimentel

doi:10.1590/s0102-695x2011005000025

Cited by 53 publications

(25 citation statements)

References 61 publications

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“…et Smith, also called Alpinia speciosa K. Schum is abundant in Northeast Brazil, where it is commonly known as "colônia". 1 The medicinal properties of this species are related to different parts of the plant, including leaves, flowers and rhizomes. 2 A field research conducted in Ibiúna, São Paulo, Brazil, revealed the use of A. zerumbet volatile fraction in respiratory disorders.…”

Section: Introductionmentioning

confidence: 99%

Development, Optimization and Validation of a GC Method by Polarity Phase Constants and Statistical Design of Experiments for the Determination of Monoterpenes in Alpinia zerumbet Essential Oil

Cardoso¹,

Nakamura²,

Correia³

et al. 2018

J. Braz. Chem. Soc.

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In this report, a rapid and selective analytical method for the determination of monoterpenes in Alpinia zerumbet essential oil (AZEO) by gas chromatography (GC) flame ionization detection (FID) was developed, optimized and validated. The suitability of six different capillary columns was investigated by polarity phase constants calculated based on the methodology proposed by Rohrschneider and McReynolds. The most suitable column was then used in a central composite design applying the following GC factors to investigate responses based on peak resolutions and analysis time: initial oven temperature, heating rate and carrier gas flow rate. The optimized method has initial oven temperature of 60 o C, heating rate of 5.1 o C min -1 and flow rate of 1.0 mL min -1 using the DB-35 capillary column. The validation acceptance criteria were met in all cases. The method was successfully applied for the quantification of major monoterpenes found in AZEO in different samples of Alpinia zerumbet.

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Section: Introductionmentioning

confidence: 99%

Development, Optimization and Validation of a GC Method by Polarity Phase Constants and Statistical Design of Experiments for the Determination of Monoterpenes in Alpinia zerumbet Essential Oil

Cardoso¹,

Nakamura²,

Correia³

et al. 2018

J. Braz. Chem. Soc.

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“…These species have been commercialized in the food and cosmetic industries. However, their greatest importance arises from the medicinal properties of their essential oils which have been used in folk medicine (Victório, 2011). Some studies have reported different pharmacological properties of the essential oil of A. zerumbet, such as antihypertensive (Lahlou et al, 2003), antinociceptive (de Araújo et al, 2005), anxiolytic (Satou et al, 2010), antipsychotic and antioxidant (de Araújo et al, 2011) attributes.…”

Section: Introductionmentioning

confidence: 99%

Genetic toxicology evaluation of essential oil of Alpinia zerumbet and its chemoprotective effects against H2O2-induced DNA damage in cultured human leukocytes

Cavalcanti

Ferreira

Cabral

et al. 2012

Food and Chemical Toxicology

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Essential oil (EO) of Alpinia zerumbet leaves, at non-toxic concentrations (50-300 μg/mL), did not induce genotoxicity in human leukocytes. However, at the highest concentration (500 μg/mL) tested caused a reduction in cell proliferation and viability, and an increase in DNA damage. Moreover, in vivo experiments showed that EO (400 mg/kg) did not exert mutagenicity on peripheral blood cells and bone marrow in mice. In DPPH test, EO showed scavenging effects against DPPH radicals, and other free radicals (determination of intracellular GSH and lipid peroxidation assays). Furthermore, EO was able to reduce the intracellular levels of ROS, and prevented leukocytes DNA against oxidative damage. The ability of EO to reduce H(2)O(2) toxicity was observed only when cells were treated with EO during and after exposure to H(2)O(2). With the co- and post-treatment procedures, EO decreased the frequency of apoptotic and micronucleated leukocytes as well DNA strand breaks. However, a synergistic effect was observed in cultures exposed to 500 μg/mL EO. In conclusion, EO at concentrations up to 300 μg/mL or doses up to 400mg/kg are not mutagenic in leukocytes and in mice, but do have antioxidative and protective effects against the cytotoxicity and clastogenesis induced by H(2)O(2).

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“…In folk medicine, A . zerumbet has a wide spectrum of traditional uses, ][ a fact that appears through its creole denominations ‘atoumo’ meaning ‘against all pains’, as well as ‘guérit‐tout’ meaning ‘cures everything’ . ][ Releasing a ginger‐like aroma, the rhizome is used notably as a tonic and a stimulant in various forms such as macerations, infusions, tinctures, etc …”

Section: Introductionmentioning

confidence: 99%

“…][ In Brazil, the tea made from A . zerumbet leaves is recommended as an antihypertensive medication and presents diuretic, spasmolytic, bacteriostatic/bactericide, fungistatic, anti‐inflammatory, antioxidant, and antiulcerogenic effects . ][ …”

Section: Introductionmentioning

confidence: 99%

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Chemical Composition, Antimicrobial and Insecticidal Activities of Flowers Essential Oils of Alpinia zerumbet (Pers.) B.L.Burtt & R.M.Sm. from Martinique Island

Kerdudo

Ellong

Burger

et al. 2017

Chemistry & Biodiversity

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Alpinia species, used as ornamental plants and flavoring agents, are renowned for their therapeutic properties and their subsequent use in traditional medicines throughout the world. Alpinia zerumbet (Pers.) B.L.Burtt & R.M.Sm. is the most common Alpinia species encountered in Martinique. Several essential oils (EOs) obtained by hydrodistillation of A. zerumbet flowers collected in various locations on the island at different seasons were analysed to evaluate the influence of the collection period and area on the EOs' chemical compositions and to assess their bioactivity. A combination of GC-FID and GC/MS techniques was used to examine the volatile constituents, leading to the identification of a total of 71 components accounting for 97.8 - 99.3% of the respective total GC-FID areas: among them, nineteen compounds were characterized for the first time in A. zerumbet EOs. The antimicrobial activity of these EOs was assessed against eight bacterial, yeast and fungal strains and two multi-resistant strains: some significant bacteriostatic and fungistatic activities of A. zerumbet flower oils were evidenced. Finally, an interesting insecticidal activity of the flower EO was highlighted for the first time against Aedes aegypti.

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Therapeutic value of the genus Alpinia, Zingiberaceae

Cited by 53 publications

References 61 publications

Development, Optimization and Validation of a GC Method by Polarity Phase Constants and Statistical Design of Experiments for the Determination of Monoterpenes in Alpinia zerumbet Essential Oil

Development, Optimization and Validation of a GC Method by Polarity Phase Constants and Statistical Design of Experiments for the Determination of Monoterpenes in Alpinia zerumbet Essential Oil

Genetic toxicology evaluation of essential oil of Alpinia zerumbet and its chemoprotective effects against H2O2-induced DNA damage in cultured human leukocytes

Chemical Composition, Antimicrobial and Insecticidal Activities of Flowers Essential Oils of Alpinia zerumbet (Pers.) B.L.Burtt & R.M.Sm. from Martinique Island

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