2002
DOI: 10.1590/s0102-695x2002000300043
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Abstract: Cissampelos sympodialis Eichl. (Menispermaceae) has been investigated about its botanical, chemical, pharmacological and toxicological aspects in our laboratory. Previous acute toxicology studies demonstrated that in dogs as well as in Wistar rats, 5 g/kg, p.o., and 2 g/kg, i.p. of the aqueous fraction of the ethanol extract of the leaves of Cissampelos sympodialis (AFL), induced a significant increase in the phosphatase alkaline and gama glutamil tranferase (GGT) levels, that were completely reversed in 15 da… Show more

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“…of the aqueous fraction of the ethanol extract of C. sympodialis leaves (AFL) was devoid of any toxicological effect. Similar results also were observed in dogs after an AFL subacute treatment (Diniz et al, 2002).…”
Section: Introductionsupporting
confidence: 86%
“…of the aqueous fraction of the ethanol extract of C. sympodialis leaves (AFL) was devoid of any toxicological effect. Similar results also were observed in dogs after an AFL subacute treatment (Diniz et al, 2002).…”
Section: Introductionsupporting
confidence: 86%